Join us as we detail MCAT exam topics. Each podcast covers several MCAT sections with lessons based on review material put out by the AAMC, such as practice tests and question banks. Sam also interviews MCAT tutors and experts who share tips on how premed students can raise their score to get into medical school.
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Medical education innovation for premed, medical students, physician assistants, and nursing. Mnemonics, memory palaces, speed reading, study hacks, mind maps for the MCAT, USMLE, COMLEX, PANCE, NCLEX, and all of your healthcare board exam and classroom needs!
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Physicians with admission committee experience share tips, strategies, and experiences to help premed students succeed at becoming a doctor. Guest speakers provide insight into applying to medical school, selecting a medical specialty, and applying for residency. The Prospective Doctor podcast is for anyone considering, or on the path to, practicing medicine!
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Atomic chemistry is a core component of the MCAT, essential for understanding molecular behavior and periodic trends. In this episode, host Sam Smith explores key concepts in atomic chemistry, including the intricacies of quantum theory, hybridization, and molecular geometry. You'll gain insights into electron configuration, periodic trends, and th…
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A foundational part of the MCAT, light and optics bridge the gap between physics and biology, making them vital for your exam preparation. In this episode, Sam Smith breaks down the fundamentals of light, covering both its wave and particle properties. From the energy of photons and the photoelectric effect, to wave behavior and the principles of r…
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Learning and memory are foundational concepts that play a critical role in acing the MCAT, especially in the Psych/Soc section. In this episode, host Sam Smith discusses the key concepts of learning and memory, covering the brain structures involved in memory formation, like the hippocampus and amygdala, as well as the different types of memory—exp…
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Study Types and Research Design
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47:25
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47:25
Understanding study design and research variables is crucial for mastering the MCAT and in medical research. In this episode, host Sam Smith discusses the essentials of study design and research methods, from understanding independent and dependent variables to navigating the complexities of correlation, causation, and confounding variables. You’ll…
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Organic Chemistry Mechanisms To Know
16:30
16:30
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16:30
In this episode, Sam Smith will discuss and help you understand the essential organic chemistry mechanisms and reactions you may encounter when taking the MCAT. From nucleophilic substitution reactions like SN1 and SN2 to aldol condensation and oxidation and reduction of alcohols, Sam will cover the high-yield topics that are crucial for your test …
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Mastering the concept of sociological groups can unlock a deeper understanding of how we interact and influence each other. On top of that, social interactions and group dynamics form the backbone of the Psych/Soc section of the MCAT, so mastering this topic is key to a good score. In this episode, host Sam Smith breaks down the essential topic of …
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Genetics: Gene Expression
53:24
53:24
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53:24
In this episode, we explore key topics in genetics, including how sex-linked and autosomal traits are inherited. We'll break down inheritance patterns using real-world examples, like X-linked recessive diseases, and walk through Punnett square problems to show how these traits are passed down. We also cover the regulation of gene expression, focusi…
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Genetics: Chromosomes, Meiosis and Mitosis, and Inheritance Patterns
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44:53
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44:53
In this episode, we cover the foundational concepts of genetics, focusing on chromosomes, mitosis, meiosis, and inheritance patterns—important topics for the MCAT Bio/Biochem section. We’ll discuss how Gregor Mendel’s laws of segregation, independent assortment, and dominance influence inheritance and how Charles Darwin’s theory of natural selectio…
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Enzyme Kinetics, Inhibition, and Categorization
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45:19
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45:19
In this episode, we explore enzyme kinetics and inhibition, key concepts for the MCAT Bio/Biochem section. We’ll cover how enzymes accelerate biological reactions by lowering activation energy and introduce two models for enzyme-substrate interaction: the lock-and-key model and the induced fit model. You'll learn how to apply the Michaelis-Menten e…
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Biomolecule Structure, Naming, And Function
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45:31
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45:31
In this episode, we’ll learn the intricate world of biomolecule structure, naming, and function. We'll explore the structural nuances between glucose and fructose and unravel the complexities of glycosidic linkages in sucrose. We'll also examine the vital roles of fatty acids, the composition of triglycerides and phospholipids, and their impact on …
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Metabolism: Gluconeogenesis, Pentose Phosphate Pathway, and More
26:11
26:11
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26:11
In this episode, we're diving deep into the nuanced aspects of metabolism that are essential yet less prominently featured on the MCAT. We'll cover gluconeogenesis, the pentose phosphate pathway, and ketone body generation—topics that, while subtle, play a crucial role in your comprehensive understanding of biochemistry. We'll explore how your body…
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Metabolism: Glycolysis, Krebs Cycle, Electron Transport Chain
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42:58
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42:58
In this episode, Sam Smith covers the intricacies of metabolism, focusing on glycolysis, the Krebs cycle, and the electron transport chain. First, the podcast explores the process of glycolysis, breaking down the key enzymes, intermediates, and regulation points. Next is the citric acid cycle, examining its regulation, energy production, and the ro…
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Acids and bases are foundational topics in chemistry, crucial for understanding various biological and chemical systems you'll encounter in the MCAT. In this episode, host Sam Smith discusses the selection and use of indicators in titrations to the pH at the equivalence point and the importance of buffers in maintaining physiological pH levels. You…
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A foundational topic for the MCAT is the nervous system, appearing in several exam sections and impacting everything from neurotransmission to brain structure. In this episode, Sam Smith walks us through the nervous system, covering its major components and functions. From the organization of the central and peripheral nervous systems to neurotrans…
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Amino acids are the building blocks of life and an essential topic for the MCAT. In this episode, host Sam Smith takes us through the key concepts of amino acids, including their structures, naming conventions, and roles in protein formation. We’ll cover the differences between hydrophobic and hydrophilic amino acids, how to memorize single-letter …
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One of the body's key survival mechanisms is gluconeogenesis, a vital metabolic process, and the body's clever way of making glucose when supplies are low. On this episode of the MCAT Basics podcast, guest host Alex Starks walks through the process of gluconeogenesis. He explains how the body generates glucose when levels drop. Highlighting the liv…
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Electron Transport Chain
37:48
37:48
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37:48
The electron transport chain is a fundamental pathway in biochemistry, critical for understanding the energy production that powers cellular function. In this episode, guest host Alex Starks breaks down the intricate process of the electron transport chain (ETC). Building on previous discussions of glucose metabolism, Alex walks through the compone…
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One of the most fundamental biochemical processes is the Krebs cycle. This metabolic pathway plays a critical role in both the Chem Phys and Bio/Biochem sections of the MCAT, so understanding it is key. In this episode, our guest host, Alex Starks, walks us through the transformation of pyruvate into acetyl CoA via the Pyruvate Dehydrogenase Comple…
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In this episode, guest host Alex Starks introduces the Metabolism series by examining glycolysis, a fundamental biochemical pathway for energy production. The discussion covers glucose digestion, the role of insulin and glucose transporters, and the step-by-step breakdown of glucose within cells. Alex also offers a detailed explanation of how gluco…
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In this episode, we focus on biosignaling and cover how cells communicate through systems like voltage-gated and ligand-gated ion channels, using real-world examples such as neuronal signaling and muscle contraction. We also break down the role of enzyme-linked receptors, specifically receptor tyrosine kinases (RTKs), and explore how these pathways…
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In this episode, guest host Alex Starks dives into Gas-Phase Concepts for the MCAT. He breaks down the physical properties of gases, explores the ideal gas law, and unpacks the ABCD laws of gases. Alex also covers key conditions that influence molecular collisions in gases and highlights the most important takeaways to help you excel in this sectio…
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In this episode, we focus on the lymphatic system, a crucial topic for the Bio/Biochem section of the MCAT. We'll cover the structure of the lymphatic system, including lymphatic vessels, lymph nodes, and major organs such as the bone marrow and thymus. You'll also learn about the system’s primary functions: returning fluid to the blood, supporting…
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Psychological Disorders
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50:03
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50:03
In this episode, we dive into psychological disorders, a crucial topic for the Psych/Soc section of the MCAT. We’ll start by defining what a psychological disorder is, highlighting key concepts like significant stress and deviant behavior, and discussing how they’re classified using the DSM-5. You'll learn about various categories of disorders, inc…
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The Respiratory System
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45:38
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45:38
In this episode, we cover the respiratory system, an important topic for the MCAT Bio/Biochem section. We'll go over the anatomy of the respiratory system, highlighting key structures such as the lungs, bronchi, bronchioles, and alveoli, and explain how they contribute to respiratory functions. You'll also learn about the main roles of the respirat…
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DNA Mutations and Repair
53:46
53:46
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53:46
In this episode, we focus on DNA mutations and repair, a key topic for the Bio/Biochem section of the MCAT. We'll cover the different types of mutations, including point mutations, insertions, and deletions, and explain how they occur due to replication errors or environmental factors like UV radiation. You'll also learn about the repair mechanisms…
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In this episode, we focus on the structure and role of key social institutions for the MCAT Psych/Soc section. We'll break down the five major institutions—health and medicine, education, family, religion, and government—and explain how each shapes societal norms and individual behavior. You’ll learn about concepts like medicalization, the sick rol…
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In this episode, we break down aromatic compounds, a crucial topic for the Biochem and Chem/Phys sections of the MCAT. You’ll learn what makes a compound aromatic, how to identify them using Huckel’s Rule, and the difference between aromatic, antiaromatic, and nonaromatic compounds. Sam Smith covers key examples like benzene, toluene, and phenol, a…
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Aging is an essential topic for the MCAT, and in this episode, we’ll explore it from multiple angles. We start with the biological aspects of aging, including key processes like telomere shortening, cell senescence, and mitochondrial dysfunction—each providing insight into how and why cells age. From there, we dive into how aging impacts the brain,…
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In this episode, we focus on personality and the theories relevant for the MCAT. We’ll cover key perspectives, such as psychoanalytic theory, humanistic theory, and trait theory, along with the influence of social cognitive and biological factors on personality development. You’ll get an overview of the different personality disorders, categorized …
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Molecular Structure and Absorption Spectra
37:14
37:14
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37:14
In this episode, we cover molecular structure and the key spectroscopy techniques you need to know for the MCAT. We'll explore the intricacies of Nuclear Magnetic Resonance spectroscopy, breaking down the chemical shifts and spin-splitting essentials for understanding hydrogen and carbon bonds in various compounds. You'll learn how to identify func…
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The Doppler Effect is a crucial concept for the MCAT, particularly in the Chemistry & Physics section. We'll explore how the Doppler effect occurs when a wave source moves relative to an observer, affecting the observed frequency and wavelength. Using practical examples like an ambulance speeding towards you, we'll bring these concepts to life. We'…
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In this episode, we cover the topic of viruses. We explore a comprehensive range of subtopics including the definition and structure of viruses, their life cycles, and the differences between transduction and transfection. We also discuss virus classification, viral mutations, and subviral particles. This material will primarily appear in the Bio/B…
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In this episode, we cover the topic of work and energy. We’ll start off by talking about work, which includes the mathematical and conceptual definitions and the sign convention of work. We’ll also talk a little bit about mechanical advantage and also path dependency. Moving on to energy, we’ll talk about the general definition of energy, we’ll com…
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Fat and Protein Metabolism
37:09
37:09
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37:09
In this episode, we’ll nail down all that is needed for the MCATB in relation to fat and protein metabolism. Two critical processes for gaining energy and maintaining cellular functions in the body. We'll learn about the intricate details of beta-oxidation, where fatty acids are broken down in the mitochondrial matrix to produce energy-rich molecul…
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Social Norms & Deviance
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32:16
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32:16
Social norms and deviance as covered in the MCAT is a fascinating topic, and in this episode, we'll break down the intersection of social norms—folkways, mores, taboos, and laws—how they play a crucial role in shaping societal values, and what happens when these norms break down, a concept known as anomy. Plus, we'll delve into collective behavior …
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In this episode, we discuss population genetics and see how genetically related individuals share the same alleles, delving into the mechanisms of gene flow and genetic drift. We'll also unravel the complexities of hybrid vigor, reproductive isolation, and natural selection, and how these processes shape the genetic landscape of populations. We'll …
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In this episode, we'll explore three crucial hormone axes: the hypothalamic-pituitary-adrenal (HPA) axis, the hypothalamic-pituitary-gonadal (HPG) axis, and the renin-angiotensin-aldosterone (RAAS) system. We'll decode the complex interplays among the hypothalamus, pituitary gland, and various peripheral organs, focusing on how these hormone system…
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In this episode, we're covering the anatomy and physiology of key organs such as the kidneys, liver, skin, lungs, and large intestine, and discuss the crucial role they play in eliminating waste products from our bodies. From the structure of the hepatic lobules in the liver to the sweat glands in our skin and the alveoli in our lungs, we'll cover …
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Sleep and Circadian Rhythms
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45:40
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45:40
This episode is packed with essential high-yield information for your MCAT prep, covering the biological, physiological, and psychological aspects of sleep. We’ll explore various sleep theories, like the Memory Consolidation and Brain Plasicticity Theories, and even discuss the controversial “Sleeping When You Die” theory. We’ll also delve into dre…
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In this episode, we’ll cover crucial aspects such as hormones, their origins and mechanisms of action, and the various structures within the endocrine system. We'll also decode complex cell-to-cell communication and distinguish between different hormone types—peptide, protein, steroid, and lipid-derived. Furthermore, we'll explore key endocrine dis…
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In this episode, we'll break down the intricate processes of nutrient digestion and absorption, from the mechanical and chemical digestion in the stomach to the vital role of the small and large intestines. We'll also discuss the regulatory mechanisms involving hormones and nervous innervation and the essential structures like the liver, gallbladde…
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In this episode of MCAT Basics, we’ll cover Electrochemistry. We start with the role of salt bridges in electrochemical cells and cover the intricacies of cell notation. We’ll also discuss how ions maintain charge balance, the importance of reduction and oxidation potentials, and how these elements come together in galvanic and electrolytic cells. …
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This MCAT Basics podcast covers biological membranes. First, the podcast introduces a few topics regarding membranes: what they are, how they are formed, their presence in the cell, and cell-to-cell junctions. Second, it addresses transport through the membrane, including simple diffusion, active vs. passive transport, and transport membrane protei…
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Adenosine Triphosphate or ATP
48:47
48:47
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48:47
In this episode, we’ll talk about ATP or adenosine triphosphate. We will begin with a detailed examination of ATP's structure and composition as a nucleotide, followed by an explanation of the metabolic pathways involved in its production—both aerobic and anaerobic. We will also cover the pivotal process of ATP hydrolysis, emphasizing its energy re…
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In this episode, we explore the topic of intelligence, which is primarily featured in the psychology and sociology section of the MCAT. We cover several key theories, including entity vs. incremental theory, general intelligence theory, two-factor theory, multiple intelligences theory, Triarchic theory, CHC theory, and biological theories. Addition…
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Redox Reactions: Reduction and Oxidation
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46:54
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46:54
Redox reactions or reduction and oxidation are reactions in which electrons are simultaneously transferred from one chemical species to another. This episode begins with exploring this concept, including an in-depth look at oxidizing and reducing agents and the factors determining a compound's effectiveness as an oxidizing agent. It also covers the…
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In this episode, we focus on the physiology of sound and hearing. We begin by exploring sound-related concepts, including sound waves, pitch, ultrasound, and the decibel system. Next, we delve into the anatomy and physiology of the ear, providing a clear understanding of how we perceive sound. This material will appear in two of the four MCAT secti…
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Protecting Your Physician Credentials with Dr. Leah Houston
23:41
23:41
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23:41
Imagine your credentials as a physician being misused, making it impossible for you to work. Dr. Leah Houston went through this identity theft nightmare. This experience led her to start HPEC, a decentralized autonomous organization of practicing physicians—essentially a digital physician guild. Dr. Houston, an emergency medicine physician turned p…
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This MCAT Basics episode covers fluid statics (fluids standing still). It begins with different fluid properties, including surface tension, vapor pressure, adsorption and absorption, adhesion and cohesion, and Henry's law. Next, it discusses several important fluid statics concepts: static fluid pressure, Pascal's law, gauge pressure vs absolute p…
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This MCAT BAsics episode covers the muscular system. It begins with the differences and similarities between the three types of muscle (smooth, cardiac, and skeletal). Then, the podcast explores the basic structure of a skeletal muscle cell and the various organelles unique to this cell type, including the sarcolemma, sarcoplasm, myofibrils, sarcom…
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