Blood, Sweat and Smears is a podcast focused on thrombosis and hemostasis and is hosted by Benign Hematologist, Dr. Brad Lewis. Dr. Lewis shares some of his knowledge built over decades of experience in hematology and laboratory testing.
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We live in a world driven by data, and every day, innovative, ground-breaking tests, solutions, and tools generate millions of healthcare data points. But how do we transform that information into knowledge and insights that enhance patient care? Join entrepreneurial, innovative, and forward-thinking physician, Dr. Pat Alagia as he speaks with top researchers, doctors, and thought leaders about the hottest topics in healthcare. From the latest in cutting-edge research to what’s coming next i ...
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In this episode of Blood, Sweat and Smears, our senior director of Business Development, Bjorn Stromsness, attended the American Society of Nephrology (ASN) Kidney Week 2024 in San Diego, CA, and asked nephrologists 1 question: what is the most critical test you order for your patients? For more information on Machaon Diagnostics and the testing we…
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5 Questions with Dr. Xiao Peng
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5 Questions is a new series of Blood, Sweat and Smears, hosted by our Senior Director, Bjorn Stromsness, who asks 5 questions to physicians in and around the disease areas we work in. In this episode, we are joined by Dr. Xiao Peng, who recently joined the Children’s Hospital at Montefiore faculty as Assistant Professor in the Division of Genetics,…
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Part 2: The Future of Laboratory Diagnostic Medicine
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In this episode of Diagnostics Dialogues - Innovation & Insight, Dr. Pat Alagia is joined by two brilliant Quest colleagues, Senior Surgical Pathologist and Cytopathologist Dr. Elena Enbom, and Managing & Medical Director of Anatomic Pathology & Director of The Center of Excellence for Digital & AI-Empowered Pathology, Dr. Piotr Borkowski. Together…
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5 Questions with Dr. Anita Dhanrajani
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11:54
5 Questions is a new series of Blood, Sweat and Smears, hosted by our Senior Director, Bjorn Stromsness, who asks 5 questions to physicians in and around the disease areas we work in. In this episode, we are joined by Dr. Anita Dhanrajani, a pediatric rheumatologist at Children's Hospital New Orleans, specializing in children with autoimmune diseas…
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Part 1: Molecular Expression Through The Eyes Of The Pathologist And Oncologist
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In this installment of our two-part series on the fundamental pillars of laboratory-based diagnostic patient care, Dr. Pat Alagia is joined by two of the top minds in laboratory medicine and anatomic pathology, Dr. Hope Karnes and Dr. Darren Wheeler. Offering a deep dive into the evolving world of pathology, they bring to light how the work of path…
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5 Questions with Dr. Gefen
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11:17
5 Questions is a new series of Blood, Sweat and Smears, hosted by our Senior Director, Bjorn Stromsness who asks 5 questions to physicians in and around the disease areas we work in. In this episode, we are joined by Dr. Ashley Gefen, MD, a pediatric nephrologist specializing in genetic kidney diseases, tubular disorders, and kidney stone disease a…
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5 Questions with Dr. Kopko
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5 Questions is a new series of Blood, Sweat and Smears, hosted by our Senior Director, Bjorn Stromsness who asks 5 questions to physicians in and around the disease areas we work in. In this episode, we are joined by Dr. Patricia Kopko, a Professor of Pathology at UC San Diego, Director of Transfusion Medicine, and Associate Director of the Immunog…
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In this podcast our Medical Director, Dr. Brad Lewis, discusses mixing studies- more specifically what a mixing study is and what it isn't, as well as a few quirks we see in some of the mixing studies. Click here ➡️ https://bit.ly/47wN5fN for information on all the different mixing studies that Machaon Diagnostics performs.…
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Diagnosing Heparin-Induced Thrombocytopenia (HIT) and the role of HIPA Testing
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In this podcast, our Medical Director, Dr. Brad Lewis, discusses heparin-induced thrombocytopenia, also known as HIT. Dr. Lewis addresses what HIT is, how to diagnose and interpret testing, and the role of functional testing like the HIPA (Heparin-Induced Platelet Antibody) test.Dr. Brad Lewis, Machaon Diagnostics
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A Commitment To Women’s Health
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47:34
Welcome to Diagnostics Dialogues - Innovation & Insight, where we are covering the hottest topics in healthcare with top researchers, doctors, and thought leaders! For this episode, Dr Pat Alagia is joined by Vice President & General Manager of Women’s and Reproductive Health at Quest Diagnostics, Kathleen Valentine, and Quest's Director and Medica…
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Diagnosing and treating Hemophagocytic lymphohistiocytosis (HLH)
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In this podcast, our Medical Director, Dr. Brad Lewis, talks with Dr. Scott Canna, from the Division of Rheumatology and the Immune Dysregulation Program at Children's Hospital of Philadelphia. Dr. Lewis and Dr. Canna discuss Hemophagocytic lymphohistiocytosis (HLH); what HLH is, treating and diagnosing HLH, and infections that make you particularl…
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Growing as a Laboratory Partner
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29:08
Welcome to Diagnostics Dialogues - Innovation & Insight, where we are covering the hottest topics in healthcare with top researchers, doctors, and thought leaders! In this episode, Dr Pat Alagia is joined by Mike Lukas, Vice President and General Manager of Health Systems at Quest Diagnostics. Mike has led considerable growth at Quest, leading to i…
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Diagnosing and treating aHUS in a 40-day-old patient
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In this podcast, our Medical Director, Brad Lewis, discusses a pediatric case of aHUS with Dr. Amara Finch, a Pediatric Resident Physician at the University of Utah. Dr. Finch presents a fascinating case of atypical hemolytic uremic syndrome (aHUS) in a 40-day-old patient. Using Machaon Diagnostics' fast turnaround time, physicians were able to get…
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Commitment to Employee Health: A Blueprint for Wellness
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32:45
Welcome to Diagnostics Dialogues - Innovation & Insight, where we are covering the hottest topics in healthcare with top researchers, doctors, and thought leaders! In this episode, Dr Pat Alagia is joined by Dr Steve Goldberg, Vice President, Chief Health Officer, Employee and Population Health at Quest Diagnostics. Dr Goldberg is a brilliant physi…
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Exploring Digital Pathology and Artificial Intelligence
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Welcome back to another episode of Diagnostics Dialogues - Innovation & Insight, where we are covering the hottest topics in healthcare with top researchers, doctors, and thought leaders. Today, host Dr Pat Alagia is speaking with Dr Darren Wheeler, Vice President of Pathology and Medical Services at Quest Diagnostics. Dr Wheeler joins us to discus…
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Disease Surveillance: Preventing the Next Pandemic
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Welcome to Season 2 of Diagnostic Dialogues - Innovation & Insight, where we are covering the hottest topics in healthcare with top researchers, doctors, and thought leaders! Today, host Dr Pat Alagia is joined by Dr Hema Kapoor and Dr Robert Jones to discuss disease surveillance! The trio talk about why COVID took the world by surprise and what th…
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Tune in to Season 2 of Diagnostic Dialogues - Innovation & Insight and join entrepreneurial, innovative, and forward-thinking physician, Dr Pat Alagia as he speaks with top researchers, doctors, and thought leaders about the hottest topics in healthcare. From the latest in cutting-edge research to what’s coming next in the world of diagnostic medic…
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Renal transplants and the roles of testing around it
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In this podcast, our Medical Director, Brad Lewis, talks with Dr. Christina Klein, a transplant nephrologist and the head of the transplant program at Piedmont Transplant Institute in Atlanta, GA. Dr. Lewis and Dr. Klein discuss renal transplants and the different roles of testing around renal transplants (i.e. gene sequencing and soluble MAC). The…
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Alzheimer’s disease: A new generation of screenings and therapies on the horizon
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The number of Americans living with Alzheimer's Disease (AD) continues to grow at an exponential rate. Currently, more than 6 million Americans have AD, and that number is expected to double by 2050. But recent research findings are beginning to show the important role diagnostics may play in the next era of AD. New diagnostic innovations could unl…
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Understanding next-generation sequencing (NGS)
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In this podcast, our Medical Director, Brad Lewis, continues his conversation with Jamey Kain, Vice President of Genetic Innovation here at Machaon. Brad and Jamey discuss what next-generation sequencing (NGS) is, why it's important and some of the issues we face with NGS. Don't forget, Machaon offers genetic testing STAT results in 48 hours!…
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The successful convergence of clinical and operational thinking in the lab
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In today’s healthcare environment, laboratory leaders are required to provide the highest quality services to support improved patient outcomes. To succeed, they must implement scalable medical, analytical, and operational strategies, all while driving and balancing fiscal excellence and responsibility. In this episode, host Dr Pat Alagia, Senior M…
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How to choose panels for next-generation sequencing (NGS)
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In this podcast, our Medical Director, Brad Lewis, talks with Jamey Kain, Vice President of Genetic Innovation here at Machaon. Brad and Jamey discuss how we design our genetic panels, what goes in, what stays out and how we think about clinical utility and turnaround time considerations. Don't forget, Machaon offers genetic testing STAT results in…
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Achieving the Triple Aim through the power of strong laboratory partnerships
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Health systems and laboratory diagnostics leaders are exploring new strategies and solutions to help enhance patient and population health and to deliver value to their organizations. In this episode, Dr Pat Alagia and Mike Lukas discuss: The clinical, operational, and business complexities health systems currently face How strong laboratory partne…
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The view from the top: Looking back and ahead in 2022
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The COVID-19 pandemic continues to drastically disrupt the healthcare industry. At the same time, it has shone a light on the most pressing issues within its ecosystem, setting in motion the beginning of a new era of crucial changes and innovation. In this session, Dr Alagia and Dr Wohlgemuth discuss: The key role played by Quest in response to the…
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The power of laboratory analytics
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31:44
Diagnostics is the thread that connects the entire healthcare ecosystem and patient care continuum. And the laboratory generates an immense amount of data that can help enable improvements in both patient and hospital health. By better leveraging laboratory analytics, health systems and clinicians can identify, stratify, and prioritize patient popu…
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Psychological and Emotional Impact of VTE Diagnosis; Improving Patient Outcomes
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Join Dr. Kerstin de Wit and our Medical Director, Dr. Brad Lewis, discuss the importance of accessing and educating patients with newly diagnosed venous thrombotic disease. Many patient factors, including age, sex, activity and knowledge levels should be considered to optimize acceptance and disease management. Providers can help patients minimize …
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From CLS to CEO, the story of Machaon Diagnostics
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In this episode we hear an interview with Mike Ero, Machaon Diagnostics' Founder and CEO. A Clinical Laboratory Scientist (CLS) who added an MBA, Mike started Machaon Diagnostics back in 2003 at the age of 29. Just how did all of that come about? Listen and find out. We hope you find our origin story interesting. You'll get a good sense of why we w…
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Bleeding Disorders in Women: Considerations pre, during & postpartum
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32:32
Andra James, MD, MPH is a Professor of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine at Duke University Center, and consulting professor of Medicine, Division of Hematology. She is also the founder of Duke University's Women's Hemostasis and Thrombosis Clinic. Dr. James and Machaon Diagnostics' Medical Director, Dr. Brad Lewis, discu…
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Trends in drug testing resulting from the COVID-19 pandemic
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The convergence of the opioid epidemic and the coronavirus disease 2019 (COVID-19) pandemic has created new healthcare challenges. Health systems, from a system- and individual clinician-level, are more important than ever in the pursuit of addressing the epidemic within the pandemic. In this session, Dr Gudin discusses: Recently-published data by …
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Patient-minded Neurology
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39:42
This episode features Dr Michael Racke discussing the evolution of treating neurologic disease to detect disease early and focus on prevention. In this session, Dr Racke discusses: How diagnostics and treatment has evolved for multiple sclerosis Treating patients at the first incidence of neurologic disease for optimal outcomes How health systems c…
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Optimize Oncology Care with Clinical Pathways
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This episode features Yuri Fesko MD, with clinical pathways to help guide diagnosis and treatment in oncology. In this session, Dr Fesko discusses: How clinical pathways can make an impact for hospitals to improve oncology outcomes The critical importance of collaboration for pathologists and oncologists The future of oncology care in integrated he…
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COVID-19 VITT - What we know so far
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Our Medical Director, Brad Lewis, MD, discusses COVID-19 Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT) and diagnostic strategies.Dr. Brad Lewis, Machaon Diagnostics
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COVID-19: Supporting Safety for the Front Line
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Today’s podcast features Dr Nicholaos Bellos with strategies that are helping some health systems best operate in today's healthcare environment. In this session, Dr Bellos discusses: The ease of viral transmission and what health systems can do to mitigate risk Diagnostic solutions, guidelines, and best practices to ensure safety for the front lin…
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When we asked Dr Alagia his goals for this podcast, he told us, "I think the podcast project gives our doctors and our scientists at Quest a voice. It connects us with the outside community. We work with a lot of folks who live in the laboratories, who live in the hospitals, who do great work here. It's essential work. Everything starts with the la…
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PAI-1 with Dr. Brad Lewis
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In this episode Dr. Brad Lewis talks about PAI-1, testing for PAI-1 and where things look to be heading for the future of this gene and conditions associated with it. We released this episode to coincide with Pi Day (3.14).Dr. Brad Lewis, Machaon Diagnostics
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Challenges in diagnosing Hemophagocytic Lymphohistiocytosis (HLH)
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32:11
Join Michelle Hermiston, MD, PhD - Associate Professor of Pediatrics (Pediatric Hematologist/Oncologist) at UCSF and our Medical Director, Brad Lewis, MD, discuss the challenges of diagnosing Hemophagocytic Lymphohistiocytosis or HLH, possible triggers and approach to management. If you are interested in our 48-hour STAT check out the link for more…
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Our Medical Director, Brad Lewis, MD, discusses aHUS/TMAs in pregnancy with Richard Burwick, MD, MPH - Assistant Professor, Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Cedars-Sinai Medical Center. If you are interested in our 48-hour STAT aHUS Testing please let us know. We can send you draw kits and are happy to t…
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Our Medical Director, Brad Lewis, addresses a number of questions around hypercoagulability and COVID-19.Dr. Brad Lewis, Machaon Diagnostics
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Dr. Brad Lewis discusses sC5b-9 in this podcast addressing; what sC5b-9 testing is, why you want to know about this test and when to use it. Dr. Lewis also explores how it helps when trying to confirm a diagnosis.Dr. Brad Lewis, Machaon Diagnostics
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Hemophagocytic lymphohistiocytosis (HLH)
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Dr. Brad Lewis discusses hemophagocytic lymphohistiocytosis (HLH); when you want to think about HLH, why you want to think about HLH, and how to diagnose this disorder.Dr. Brad Lewis, Machaon Diagnostics
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Blood, Sweat and Smears - Post-Bone Marrow Transplant TMA
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Dr. Lewis discusses TMAs in the post-BMT setting, recent research into the topic, when to think about it and what to do about it.Dr. Brad Lewis, Machaon Diagnostics
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Hypercoagulability explained for patients
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Dr. Brad Lewis, Machaon Diagnostics
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Dr. Brad Lewis, Machaon Diagnostics
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Hypercoagulability Testing
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19:49
Dr. Brad Lewis, Machaon Diagnostics
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Lab Testing for Patients Taking Hemlibra (Emicizumab-kxwh)
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Dr. Brad Lewis, Machaon Diagnostics
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Blood, Sweat and Smears - Common errors and misconceptions around coagulation
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Dr. Brad Lewis, Machaon Diagnostics
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Blood, Sweat and Smears - What to make of an equivocal aHUS result
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36:02
Dr. Brad Lewis, Machaon Diagnostics
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Blood, Sweat and Smears - Diagnosing Thrombotic Microangiopathies
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16:13
Dr. Brad Lewis, Machaon Diagnostics
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Dr. Brad Lewis discusses considerations for genetic testing when it comes to hemophilia and rare forms of von Willebrand disease.Dr. Brad Lewis, Machaon Diagnostics
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Blood, Sweat and Smears - Heparin Induced Thrombocytopenia
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Dr. Brad Lewis talks through how he thinks about Heparin Induced Thrombocytopenia (HIT) and when testing is called for. Dr. Lewis leverages his decades of clinical experience to help clinicians approach patients suspected of having HIT.Dr. Brad Lewis, Machaon Diagnostics
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