A podcast about the body's defenders against disease.
Become a Paid Subscriber: https://anchor.fmevelyn-eve4/subscribe Become a Paid Subscriber: https://anchor.fm/evelyn-eve4/subscribe Become a Paid Subscriber: Support this podcast: https://anchor.fm/evelyn-eve4/support
Awesome summary of the immune system Cover art photo provided by Patrick Hendry on Unsplash: https://unsplash.com/@worldsbetweenlines
Discussing all types of diabetes with various people in the diabetes community including diabetics, diabetic athletes, medical professionals who specialise in diabetes and companies and organisations who work in the diabetes industry.
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i-MPACT (Immune-Mediated Pathophysiology & Clinical Triage)


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i-MPACT (Immune-Mediated Pathophysiology & Clinical Triage)
John Walker MD PhD FRCPC
This podcast series introduces i-MPACT, a multifaceted program which aims to improve the care of patients treated with immunotherapy, while providing a better understanding of the pathophysiology associated with immune-related adverse events. Each episode features an interview with a leading expert discussing proactive, longitudinal care, as well as the potential for irAEs following treatment with immunotherapy and current toxicity management strategies.
A monthly podcast with a focus on the use and application of T and B cell receptor repertoires in diagnostics and other clinical settings.
The immune system is extremely vital for the proper functioning of our body, and important as it is, it also remains somewhat of an enigma to many of us, scientists included. With this podcast, I try to throw some light on this topic, though I must say I’m no expert authority on it, in fact quite far from it, I’m just as clueless as anyone else.
I said the nerve test wasn't so bad it was just when he pulled out the needles and that's when things got very interesting and they do hurt so I just wanted to let you guys know that namaste....--- Send in a voice message: https://anchor.fm/evelyn-eve4/messageSupport this podcast: https://anchor.fm/evelyn-eve4/support…
Skin symptoms are common in people with lupus it affects 70% to 80% of the people who have this condition the first sign is 20% of people with lupus slee is a general system general symptoms are fever headache loss of appetite and weight you also get fatigue with this also alone come with lupus you get muscles joint pains small joints like that han…
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Immune


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Immune 65: Infection infidelities with Jonathan Kagan
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Jon joins Immune to discuss the research of his laboratory on understanding how the innate immune system recognizes and responds to pathogens, and his hypothesis that infection infidelities drive innate immunity. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Guest: Jonathan C. Kagan Subscribe (free): Apple Podcasts, Go…
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Immune


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Immune 64: A tangled web of wires
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Cindy, Steph, Brianne, and Vincent do a rapid review 11 immunology papers, including a wiring diagram for the immune system, group A streptococcus vaccines, systems immunology prediction of vaccines, class switch towards IgG4 after SARS-CoV-2 mRNA vaccination, very bad B cells, monoclonal antibody to two streptococcal M protein epitopes, transcript…
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Dealing With Multiple Immune Deficiencies


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Scleroderma and Treatment part 2
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Scleroderma is a autoimmune disease that attacks your internal organs there's no cure for it but it's best that you get tested talk to your rheumatologist your internal medicine doctor or primary Care to find out the best treatment for you in no with the scleroderma I just discussing know the different things that I use to help me with my scleroder…
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Dealing With Multiple Immune Deficiencies


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Scleroderma and Symptoms part 1.
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Scleroderma is a long lasting autoimmune disease that affects the skin connective tissues internal organs skin can get tightened and thick scarring from on the lungs and kidney blah blah vessels May thicken and stopped working the way they should so you can get tissue damage and high blood pressure thank you all for being here with me on this journ…
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Dealing With Multiple Immune Deficiencies


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Lupus Symptoms in women early signs
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If we don't now Lupus is and autoimmune Diseases that means the body attack its own cells and organs also the skin joints,heart, lungs, blood, kidneys, and the brain. Thank you all for been here with me on this journey and again Happy New years to everyone and namaste... Thank you for subscribing to my platform I really appreciate it is only $1.99 …
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OnAIRR - Immune receptors in the clinic


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OnAIRR 10: Characterising B Cell Lymphomas or Profiting from a Focus on B Cells in Health and in Disease with Dr. Ralf Küppers
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Prof. Dr. Ralf Küppers is the director of Institute of Cell Biology (Tumor Research), University of Duisburg-Essen, Germany. The work of Prof. Küppers revolves around B cell differentiation and function together with pathogenesis of human B cell lymphomas - both Hodgkin and Non-Hodgkin lymphoma. We discuss how micro-dissection and Sanger sequencing…
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Dealing With Multiple Immune Deficiencies


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5 Ways To Take Care Of Fingernail Affected By Lupus
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Prevent fungal nail Eat Healthy food to Strengthen your nailManicures and PedicuresTake care of your Hands and Feet TLCTalk with your Doctor If you want to join online My Lupus Team where we share questions and thought where we posting comments and support one altogether http://anchor.fm/evelyn-eve4/subscribe$1.99/mo.Get access to subscribers -only…
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Immune


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Immune 63: Immune, promptly
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Cindy, Steph, Brianne, and Vincent review some of their favorite immunology papers of 2022. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts. RSS, email Become a patron of Immune! Links for this episode CAR T for SLE (Nat MEd) Maternal gut microbiome induced IgG (Sci Immun…
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Dealing With Multiple Immune Deficiencies


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CBD and Lupus does it work
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We all know that lupus is a chronic autoimmune disease and it mess with your autoimmune system and attacks you good organs and turn them to bad but I have been doing a reading and researching about the CBD or does it help people with lupus and reading and stuff I've been coming across they're not a lot of research on does the CBD help people that h…
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Immune


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Immune 62: Every cell is an immune cell with De'Broski Herbert
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De’Broski joins immune to reveal his remarkable career path and the research of his laboratory on neuroimmunology and the immune response to parasite infections. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Guests D’Broski Herbert Subscribe (free): Apple Podcasts, Google Podcasts. RSS, email Become a patron of Immune!…
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OnAIRR - Immune receptors in the clinic


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OnAIRR 9: The ImmunoMind or wielding an AI for repertoire insights with Vadim Nazarov
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Vadim Nazarov is Co-Founder & CEO of the startup ImmunoMind. The company focuses on improving the design of adoptive T-cell therapies using multi-omics technologies. Vadim's career began at Dr. Dmitry Chudakov’s Laboratory of Adaptive Immunity, where he developed the now discontinued R-package TcR. The replacement package ‘immunarch’ is continuousl…
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Dealing With Multiple Immune Deficiencies


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Update on our iron infusion and what's been going on
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Just a quick update on what's been going on with the Iron infusion and what's been going on with me and I am grateful thankful for you all and Happy Thanksgiving to you all and your family and friends stay safe namaste....https://anchor.fm/evelyn-eve4/subscribe --- Send in a voice message: https://anchor.fm/evelyn-eve4/messageSupport this podcast: …
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Immune


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Immune 61: Training immune cells with Julia Bohannon and Musa Mhlanga
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From SLB22 on the Island of Hawai’i, Julia and Musa join Immune to reveal their remarkable career paths, and their research on understanding trained innate immunity. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Guests: Julia Bohannon and Musa Mhlanga Subscribe (free): Apple Podcasts, Google Podcasts. RSS, email Become…
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Dealing With Multiple Immune Deficiencies


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The Hones Truth about controlling Lupus part 2
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I'll be giving you the update on what's going on with me and talking to you all about the second part of the honest truth about controlling you're lupus and I like to thank you all for being here with me and being patient with me of getting this podcast after you guys and thank you all for sharing and liking my podcast with your friends and familie…
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Dealing With Multiple Immune Deficiencies


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The Hones Truth about controlling Lupus part:1. ((Update on Me))
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My update on when I went to my doctor's appointment and talking to you all about honesty about how to control your lupus this is part 1 and that will be a part 2 coming up and again I would like to thank you all for liking and listening and sharing my videos and I really do appreciate you all namaste...--- Send in a voice message: https://anchor.fm…
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OnAIRR - Immune receptors in the clinic


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OnAIRR 8: Engineering B cells or Giving the immune System an Optimal Starting Point with Dr. Adi Barzel
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Dr. Adi Barzel is an associate professor in the department of Biochemistry & Molecular Biology at Tel Aviv University, Tel Aviv, Israel. Adi is President at Israeli Society of Gene and Cell Therapy. Following Adi’s long standing interest in gene editing, we discuss the therapeutic potential based on Adi’s recent paper “In vivo engineered B cells se…
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Immune


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Immune 60: Immunoeducation with Sumali Pandey and Phil Mixter
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Somali and Phil join Immune to discuss their approaches to immunology education. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Guest: Sumali Pandey and Phil Mixter Subscribe (free): Apple Podcasts, Google Podcasts. RSS, email Become a patron of Immune! Links for this episode ImmunoReach ASMCUE: ASM Conference for Under…
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OnAIRR - Immune receptors in the clinic


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OnAIRR 7: Quality Controls in AIRR-Seq Assays or Handling the Catastrophe with Dr. Encarnita Mariotti-Ferrandiz
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Dr. Encarnita Mariotti-Ferrandiz is associate professor in Immunology at Sorbonne Université, Paris, France. Encarnita is Chair-Elect of the AIRR-Community. The discussion focuses on sample quality and how to assess this. We draw on two papers during the discussion: “Benchmarking of T cell receptor repertoire profiling methods reveals large systema…
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i-MPACT (Immune-Mediated Pathophysiology & Clinical Triage)


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i-MPACT Podcast – Ep. 10 - Dr. Mariam Shahidi
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In this episode, Dr. Walker chats with Dr. Mariam Shahidi, Endocrinologist from UAH. They review a shared case and discuss the impact that some potentially long-term side effects of immonotherapymay may have on patients, in relation to the pituitary gland, effects on the thyroid, and more. The i-MPACT Podcast is a series that discusses cutting edge…
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Immune


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Immune 59: Forks in the road: Th17 cells with Mandy McGeachy
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At Cornell University in Ithaca, NY, Mandy joins Immune to discuss her career and her research on understanding how Th17 cells develop and are influenced to be ‘good’ or ‘bad’ in their function. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Guest: Mandy McGeachy Subscribe (free): Apple Podcasts, Google Podcasts. RSS, e…
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Dealing With Multiple Immune Deficiencies


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Lupus Nephritis Symptoms
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It's all about a kidney disease and all the different symptoms in the stages that you can go through and like I said if you like to check out my lupus team.com namaste--- Send in a voice message: https://anchor.fm/evelyn-eve4/messageSupport this podcast: https://anchor.fm/evelyn-eve4/support
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Immune


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Immune 58: Gut B cells awry in ulcerative colitis
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Immune explains a study of three cohorts of patients with ulcerative colitis which finds major perturbations within the mucosal B cell compartment, highlighting a potential role for these cells in disease pathogenesis. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts. RSS,…
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Dealing With Multiple Immune Deficiencies


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Update on what's been going on with me
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Update information about seeing any rheumatologist or having new CT scan done for my pulmonologist and see gastroenterologist doctor--- Send in a voice message: https://anchor.fm/evelyn-eve4/messageSupport this podcast: https://anchor.fm/evelyn-eve4/support
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OnAIRR - Immune receptors in the clinic


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OnAIRR 6: Data Sharing or Finding Glory, Fame and a Big Pile of Gold with Dr. Brian Corrie and Dr. Scott Christley
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Dr. Brian Corrie is a computer scientist from Simon Fraser University in British Columbia, Canada. Brian is the Technical Director for the iReceptor Plus Project, and architect behind the iReceptor repository (https://www.ireceptor-plus.com). Dr. Scott Christley is a computational biologist from UT Southwestern, Texas, USA. Scott is the software de…
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Immune


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Immune 57: Bacteria, the new cure for wounds?
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Immune reviews data showing that in mice, skin bacteria activate keratinocytes to stimulate hair follicle regeneration and wound healing. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts. RSS, email Become a patron of Immune! Links for this episode Bacteria induce skin reg…
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Immune


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Immune 56: Flip flops on the thymic beach with Al Singer
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Al Singer joins immune to discuss mice that have their T cell immune system reversed, revealing the molecular basis for T cell lineage fate determination in the thymus. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Guest: Al Singer Subscribe (free): Apple Podcasts, Google Podcasts. RSS, email Become a patron of Immune!…
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Dealing With Multiple Immune Deficiencies


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The decision I decided to go with after getting my second and third opinion
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Hello everyone thank you all for joining me again I got the results back from the flexibility X-ray and I will be doing the third option after getting a second and third opinion the first option was not an option that was surgery that's what I wanted the second option something I did not want is injections in the neck that's not going to happen and…
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OnAIRR - Immune receptors in the clinic


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OnAIRR 5: Machine learning and AIRR or Looking for the needle in a needle stack with Dr. Lindsay Cowell and Dr. Victor Greiff
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Today we discuss machine learning with Dr. Lindsay Cowell and Dr. Victor Greiff. Machine learning is about pattern recognition and in AIRR-seq the patterns link to diseases and antigen binding. AIRR is nearly a perfect machine learning problem because the underlying patterns are unclear and complex - it is essentially looking for the needle in a ne…
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i-MPACT (Immune-Mediated Pathophysiology & Clinical Triage)


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i-MPACT Podcast - Ep. 9 - Dr. Alia Daoud
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Dr. Alia Daoud chats with Dr. John Walker about the respiratory and pulmonary effects of immunotherapy, using various (and very interesting!) case studies for reference. The i-MPACT Podcast is a series that discusses cutting edge research and treatments related to the immune system’s dynamic role in health and disease. It is designed with both heal…
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Dealing With Multiple Immune Deficiencies


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May is Lupus awareness a month
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Lupus awareness month you can find a lot of information on the lupus foundation.com and also beginning you a quick update on when I went to go see the surgeon and what we going to go from there and again I like to thank all you are for listening to my podcast and sharing I am so grateful and thankful for all of it I really am namaste..--- Send in a…
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i-MPACT (Immune-Mediated Pathophysiology & Clinical Triage)


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i-MPACT Podcast - Ep. 8 - Dr. Jan-Erick Nilsson
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Dr. Walker chats with Jan-Erick Nilsson, MD, LMCC, FRCPC, who is the assistant Clinical Professor at the University of Alberta's Division of Gastroenterology, Department of Medicine. They discuss the impact that immunotherapy has had in the field of gastroenterology, with a deep dive into a particular case study. A fantastic conversation that's bot…
But I was lucky enough to get in to see the surgeon today he want me to have a CT scan done with contrast because the one that they did was without the contrast and he said he needs a really clear look at the bone that's at the base of my neck and spine so he can know exactly what he's dealing with before he go in and try to repair anything but onc…
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i-MPACT (Immune-Mediated Pathophysiology & Clinical Triage)


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i-MPACT Podcast - Ep. 7 - Dr. Omar Abdel-Rahman Abdelsalam & Dr. Hatim Karichawala
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In this episode, Dr. Walker chats with Dr. Omar Abdel-Rahman Abdelsalam and Dr. Hatim Karichawala about their experiences with immunotherapy, and embark on a lively discussion about the pros and cons of the treatment. The i-MPACT Podcast is a series that discusses cutting edge research and treatments related to the immune system’s dynamic role in h…
Just want to give you all the update on what's going on I am still waiting to get in to see the surgeon we had to request for a new surgeon hopefully this week I should hear something back from them and I got up vaccination coming up for people that have Lupus and I was hoping to have been had the surgery before I have to have this vaccination but …
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i-MPACT (Immune-Mediated Pathophysiology & Clinical Triage)


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i-MPACT Podcast - Ep. 6 - Chris Brochu
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In this episode, Dr. Walker chats with melanoma survivor and immunotherapy patient Chris Brochu, who is joined by his mother Leslie Brochu and aunt, Lee Ongman. They discuss Chris' incredible journey from diagnosis to recovery, and his continued advocacy for cancer research and patient support. The i-MPACT Podcast is a series that discusses cutting…
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Immune


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Immune 55: Cells that suck at their job
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Immune reveals a CD8+ regulatory subset of T cell subset that suppress pathogenic T cells and are active in autoimmune diseases and infectious diseases including COVID-19. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts. RSS, email Become a patron of Immune! Links for thi…
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OnAIRR - Immune receptors in the clinic


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onAIRR 4: Understanding and engineering immune repertoires with Dr. Jacob Glanville
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Dr. Jacob Glanville is founder and CEO of Centivax and founder of Distributed Bio, acquired by Charles River in 2021. His work focuses on understanding and engineering the repertoires of T and B cells to improve the response to pathogens. In this episode we discuss how to analyze receptor specificity and use this to create therapeutic antibodies an…