Лучшие подкасты про Spectives (2024)

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“Monster Improvements” in CLL Care Prompt Questions About BTK Inhibitor Use 9:20

14d ago9:20

9:20

The development of noncovalent Bruton tyrosine kinase (BTK) inhibitors and other advances in chronic lymphocytic leukemia treatment signify that the “future is really exciting,” says Jennifer A. Woyach, MD, professor in the Division of Hematology at The Ohio State University in Columbus. Dr. Woyach speaks with Robert A. Figlin, MD, the Steven Spiel…

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Episode 118: Hitman Bloodmoney 1:39:05

22d ago1:39:05

1:39:05

Hitman: Blood Money, first released in 2006 by Eidos, is considered by many to be the best Hitman game ever made. After the first few games played around with novel ideas and concepts to mixed success, Blood Money honed in on the formulae of specific, small and dense environments filled with ‘accidental’ scripted opportunities to murder your target…

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“Better to Have Choices”: How New Data Transform EGFR-Mutated NSCLC Care 10:34

1M ago10:34

10:34

Given recent data, how should oncologists choose a tyrosine kinase inhibitor (TKI) in patients with EGFR-mutated non-small cell lung cancer (NSCLC), and when should chemotherapy be introduced? “It’s better to have choices than not,” explains Paul Bunn, MD, the Dudley Chair in Cancer Research at the University of Colorado in Aurora. Dr. Bunn discuss…

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Practice-Changing Data Introduce “Whole New Challenge” in Prostate Cancer 11:16

1M ago11:16

11:16

The treatment of biochemical recurrence in prostate cancer “is set for rapid development over the next few years,” says Edwin M. Posadas, MD, medical director of the Center for Uro-Oncology Research Excellence at the Samuel Oschin Comprehensive Cancer Center at Cedars-Sinai Medical Center. Data from the recent EMBARK trial have changed practice for…

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FDA Approval for TIL Therapy “Real Milestone” That Has Been “Long Time Coming” 11:26

1M ago11:26

11:26

The U.S. Food and Drug Administration’s recent accelerated approval of a tumor-infiltrating lymphocyte therapy in metastatic melanoma “is a real milestone,” after the approach was “pending for decades,” explains Jeffrey S. Weber, MD, PhD, deputy director at the NYU Langone Perlmutter Cancer Center. Dr. Weber, who was part of the team to first work …

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Episode 117: Final Fantasy VII 2:43:07

2M ago2:43:07

2:43:07

Final Fantasy VII is a landmark title not only for the JRPG genre, but for all video games. First released in 1997 and developed by Square, it took the format of the previous games and brought them to life with 3D models and environments. Featuring an ambitious and creative setting, a complicated plot with intrigue and a seemingly deep and engaging…

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From “Fairytale” to Reality? Paradigm Shift in Bladder Cancer Care 10:48

2M ago10:48

10:48

Recent advances in metastatic urothelial carcinoma have meant that optimistic outcomes are “not as much of a fairytale,” says Robert Dreicer, MD, deputy director of the UVA Cancer Center and professor of medicine and urology at the University of Virginia School of Medicine in Charlottesville. From the recent approval of enfortumab vedotin plus pemb…

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FDA Approvals, Pivotal Trial Data Change Approach to Breast Cancer Progression 11:57

3M ago11:57

11:57

Recent approvals by the U.S. Food and Drug Administration (FDA) and findings from pivotal clinical trials have changed care for patients with breast cancer that has progressed after frontline hormone therapy. Ruth M. O’Regan, MD, chair of medicine and Charles H. Dewey Professor at the University of Rochester in New York, highlights which recent dev…

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Controversies, Difficult Questions Arise in NSCLC Amid New Data 10:55

3M ago10:55

10:55

Recent data on the use of immunotherapy and targeted treatments in patients with advanced non-small cell lung cancer (NSCLC) have introduced a myriad of questions. These include controversial topics and difficult decisions, like when to incorporate CTLA-4 inhibition and what patients can expect from immuno-oncology monotherapy in the metastatic set…

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What FDA Approval of Belzutifan Means for Kidney Cancer Care 10:08

3M ago10:08

10:08

Belzutifan was recently approved by the U.S. Food and Drug Administration (FDA) for use in previously treated adults with advanced renal cell carcinoma. How should this drug best be incorporated into practice? Eric Jonasch, MD, professor in the Department of Genitourinary Medical Oncology at the University of Texas MD Anderson Cancer Center in Hous…

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Despite Lack of Head-to-Head Trials, Practice Patterns Shifting in Breast Cancer 12:04

3M ago12:04

12:04

CDK4/6 inhibitors “have really been a game changer” in metastatic breast cancer, according to Komal Jhaveri, MD, clinical director for early drug development and section head for endocrine therapy research at Memorial Sloan Kettering in New York City. However, optimal treatment strategies have been complicated by a lack of head-to-head trials. Dr. …

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S2 Ep15: PER®Spectives: Advancing Treatment in nAMD and DME with Novel Therapies 18:11

3M ago18:11

18:11

This PER®Spectives™ podcast examines opportunities for extended treatment intervals associated with newer therapies for patients with neovascular age-related macular degeneration or diabetic macular edema. In this podcast, experts Arshad Khanani, MD, Ferhina Ali, MD, and Michael Singer, MD, offer real-world data and personal insights into the use o…

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Episode 116: Rain World 2:14:43

3M ago2:14:43

2:14:43

Rain World is a game that was released to very mixed reviews. With a whopping 59 on Metacritic, it was panned for its controls, difficulty, tedium and general obtuseness. But take a gander at the community reviews and you get a very different picture. The thing is, Rain World can at times be all the things that its critics hate so much that they gi…

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Episode 115: Mailbag 5 2:33:22

4M ago2:33:22

2:33:22

It's that time of year again! For most of our episodes, our format is identical - we play a game, then discuss and review it. Once a year, however, we take a break from the format at christmas time for our Mailbag episodes. These are some of our favourite episodes to do - we take a break from the norm for some offbeat discussion about games both ol…

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S2 Ep14: Postpartum Depression: A Multidisciplinary Approach to Management 11:46

4M ago11:46

11:46

This podcast explores the diagnosis and management of postpartum depression with a focus on the importance of screening all postpartum women and treatment options. Two faculty, Sarah Nagle-Yang, MD, and Lindsey Lebin, MD, discuss the importance of an early diagnosis with each other, and a patient shares her journey living with postpartum depression…

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S2 Ep13: Patient, Provider, and Caregiver Connection™: Developing Strategies to Improve Patient Access to Care for Thalassemia - Understanding Patient Challenges and the Role of Innovative Treatment 35:14

4M ago35:14

35:14

This podcast explores the management of thalassemia with a focus on the disease burden, current therapy, and emerging gene therapy. Two faculty, Hanny Al-Samkari, MD, and Kevin H.M. Kuo, MD, MSc, FRCPC, discuss with each other and with a patient sharing their journey living with thalassemia. Faculty Hanny Al-Samkari, MD Classical Hematologist and C…

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Which FDA Approvals, Other Advances Changed ER-Positive Breast Cancer Care in 2023? 10:32

4M ago10:32

10:32

From compelling data presented at the San Antonio Breast Cancer Symposium to the recent U.S. Food and Drug Administration approval of capivasertib, 2023 saw numerous key advances in breast cancer care. Aditya Bardia, MD, MPH, director of the breast cancer research program at Massachusetts General Hospital and associate professor at Harvard Medical …

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“New Disruptor” in Prostate Cancer: PSMA PET and Other Treatment Advances 11:30

5M ago11:30

11:30

From the use of prostate-specific membrane antigen (PSMA) positron-emission tomography (PET) to advancements in targeted treatments, prostate cancer care is quickly evolving. Edwin M. Posadas, MD, director of the Experimental Therapeutics Program and director of the Center for Urologic Oncology Research Excellence at Cedars-Sinai in Los Angeles, sp…

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Practice-Changing Results in Prostate Cancer, as Enzalutamide Regimens Show Strong Benefit 11:56

5M ago11:56

11:56

Results of the recent EMBARK study show that both enzalutamide plus leuprolide and enzalutamide monotherapy significantly improved metastasis-free survival compared with leuprolide alone in patients with prostate cancer who have high-risk biochemical recurrence. Lead author Stephen Freedland, MD, associate director for education and training and di…

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Episode 114: Age of Mythology 1:33:36

5M ago1:33:36

1:33:36

Ensemble Studios blew the world away with Age of Empires way back in 1997. It took a different approach to the RTS formulae than Westwood or Blizzard, and was rewarded heavily for it. Being able to advance your entire civilization's technology level was a heady drug, and balancing the varied needs of your economy with a well rounded army was strate…

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S2 Ep12: Generalized Myasthenia Gravis: Improving Patient Outcomes Through Early Diagnosis and Management 21:10

5M ago21:10

21:10

This podcast features engaging commentary from experts in the clinical management of generalized myasthenia gravis— James Howard, Jr, MD and Nicholas Sylvestri, MD. These experts discuss the burden of disease associated with the disorder, its pathogenesis in terms of the complement system, and the clinical considerations for incorporating appropria…

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ER-Positive Breast Cancer Advances and Other Eagerly Anticipated Data at SABCS 2023 11:47

5M ago11:47

11:47

Studies involving high-risk, early-stage ER-positive breast cancer are among the most eagerly anticipated at this year’s San Antonio Breast Cancer Symposium (SABCS), to be held Dec. 5-9. Virginia Kaklamani, MD, professor of medicine in the division of hematology and medical oncology at the University of Texas Health Sciences Center San Antonio and …

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Inside ODAC’s Vote on Sotorasib in Advanced and Metastatic NSCLC: Lessons Learned 13:15

6M ago13:15

13:15

Last month, a U.S. Food and Drug Administration (FDA) Oncologic Drugs Advisory Committee (ODAC) determined that progression-free survival (PFS) could not be reliably interpreted in a confirmatory clinical trial for sotorasib (Lumakras) used to treat KRAS G12C–mutated locally advanced or metastatic non-small cell lung cancer (NSCLC). Ravi A. Madan, …

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Episode 113: Blood 1:20:38

6M ago1:20:38

1:20:38

Blood, first released in 1997 by Monolith Studios, was the middle child of the big three Build Engine games, sandwiched in between Duke 3D and Shadow Warrior. Its combination of gory horror-inspired visuals combined with action filled FPS gameplay was a huge hit at the time of release, but has slowly faded in many people’s memories. Both Quake and …

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First-Line Osimertinib Plus Chemo in NSCLC: How to Weigh Toxicity vs. Efficacy 9:15

6M ago9:15

9:15

How should results of the FLAURA2 clinical trial be applied in practice? The study examined the use of osimertinib plus chemotherapy in the first-line treatment of EGFR-mutated advanced non-small cell lung cancer (NSCLC) compared with osimertinib alone and found that progression-free survival was significantly improved with the combination treatmen…

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What Recent “Outstanding Results” in MCL Mean for Practice 11:13

6M ago11:13

11:13

“Therapies are improving dramatically” in mantle cell lymphoma (MCL), according to Michael Wang, MD, professor in the department of lymphoma/myeloma, division of cancer medicine at the University of Texas MD Anderson Cancer Center in Houston. Dr. Wang presented updates on major advances in MCL at the recent Society of Hematologic Oncology (SOHO) an…

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Episode 112: Metal Gear Solid 2: Sons of Liberty 2:11:22

6M ago2:11:22

2:11:22

Metal Gear Solid 2 was easily the most hotly anticipated game for the Playstation 2. The first game had blown everyone away, and the jaw-dropping graphics of previews combined with the quality of the animation in cutscenes seemed almost too good to be true. Luckily for fans everywhere, MGS 2 appeared to live up to its wild expectations, getting alm…

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Episode 111: Rollercoaster Tycoon 2 1:19:02

7M ago1:19:02

1:19:02

Rollercoaster Tycoon 2 was a staple of many people’s PC desktop screens back in the early 2000s. Nestled in between the big hitters like Warcraft 3 and Diablo 2 you would find this odd game that straddled the line between simulation and video game. Developed by Infogrames Interactive, it saw Chris Sawyer continue the work he put into the first game…

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The Quest to Cure CLL: “Remarkable” Results With New Strategy 16:00

8M ago16:00

16:00

Recent advances have provided new options for when and how best to treat patients with chronic lymphocytic leukemia (CLL). Trials of combination strategies have shown promise in providing patients the potential for unmaintained remissions. Marco Ruella, MD, an assistant professor of medicine in hematology-oncology at the Perlman School of Medicine …

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S2 Ep11: Advances in Topical Treatment for Presbyopia 24:11

8M ago24:11

24:11

This PER®Spectives™ podcast examines treatment of presbyopia with a focus on new and emerging topical therapies. In this podcast, experts Mile Brujic, OD, FAAO, and Jay Pepose, MD, PhD, describe these agents and how to select patients with presbyopia who will benefit from topical treatment. Faculty: Mile Brujic, OD, FAAO Premier Vision Group Bowlin…

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S2 Ep10: Multidisciplinary Perspectives on Saving Sight—The Expanding Role of the Optometrist in Retinal Disease Care 27:52

8M ago27:52

27:52

Optometrists play a critical role in first-line screening and monitoring of patients with neovascular age-related macular degeneration (or nAMD) and diabetic macular edema (or DME). Where patients require more advanced care, optometrists refer them to retina specialists. Join Drs Ferhina Ali, Carl Regillo, Jessica Steen and Mohammad Rafieetary as t…

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Episode 110: Metal Gear Solid 1:31:21

8M ago1:31:21

1:31:21

It feels like Metal Gear Solid barely needs an introduction. First released in 1998 for the playstation, it launched Hideo Kojima into the western spotlight and has been credited as a foundational game in the stealth genre. It combined a cinematic presentation with a larger than life cast of villains that somehow never broke through how seriously t…

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S2 Ep9: Clinical Pearls in Co-Managing Glaucoma 12:13

9M ago12:13

12:13

This PER® Spectives™ featured podcast examines the important role of co-management of glaucoma between optometrists and ophthalmologists .Expert faculty review the selection of traditional and novel topical therapies, and also patient selection for micro-incisional glaucoma surgery (MIGS). Faculty Danica J. Marrelli, OD, FAAO, AAO College of Optome…

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Which Data From the 2023 World Conference on Lung Cancer Are Most Likely to Change Practice? 14:18

9M ago14:18

14:18

The World Conference on Lung Cancer (World Lung) will be held in Singapore, September 9–12. The current president of International Association for the Study of Lung Cancer (IASLC), Heather A. Wakelee, MD, division chief of medical oncology at the Stanford Cancer Institute in California, shares which presentations and findings she is most looking fo…

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S2 Ep8: Advances in Treatment for Geographic Atrophy 28:33

9M ago28:33

28:33

This podcast provides a review of some of the key highlights from the Controversies in Modern Eye Care meeting held in April 2023. The program is designed for those who did not attend the live meeting and to help reinforce learnings for those who did. Faculty David S. Boyer, MD Retina-Vitreous Associates Medical Group Los Angeles, CA Tina Mac Donal…

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Episode 109: Advance Wars 1:13:16

9M ago1:13:16

1:13:16

In the 90’s turn based strategy and tactics games were everywhere, but by the turn of the millennium the RTS genre was stealing its thunder. So it was a surprise to most when in 2001 Advance Wars seemingly came out of nowhere and presented a tight and refined dose of tactics to the Western world. Its jovial and enthusiastic tone won over a lot of p…

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“Really Impactful” New Guidelines for Stage IV NSCLC With Driver Alterations 15:07

9M ago15:07

15:07

Updates to the American Society for Clinical Oncology’s (ASCO’s) living guidelines for therapy in patients with stage IV non-small cell lung cancer (NSCLC) with driver alterations were recently released. Dwight H. Owen, MD, MS, from The Ohio State University Comprehensive Cancer Center – James, examines the new recommendations that he and his team …

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More “Cage Rattling,” Less Talking: Susan Love’s Lessons for Oncologists 13:24

10M ago13:24

13:24

In early July, beloved surgeon and breast cancer advocate Susan Love, MD, MBA, died at age 75 years, after a recurrence of leukemia. Dr. Love’s legacy extends beyond the lives of her patients and into the approaches and attitudes of her fellow physicians. Stephanie Graff, MD, medical advisor to the Dr. Susan Love Foundation for Breast Cancer Resear…

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S2 Ep7: Looking at the Lid – Reducing Patient Burden in Blepharoptosis & Demodex Blepharitis 14:51

10M ago14:51

14:51

Welcome to a podcast based on learning about the lid: optimizing recognition, diagnosis, and treatment of Demodex Blepharitis and Blepharoptosis. In this podcast, we will hear from Dr Mile Brujic and Dr Cecelia Koetting. Faculty Mile Brujic, OD, FAAO Partner Premier Vision Group Bowling Green, OH Cecelia Koetting, OD, FAAO, DipABO Optometrist Denve…

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Episode 108: Bad Mojo 58:07

10M ago58:07

58:07

Power fantasies are the norm for video games. We play them to blow off steam, to escape into another world where we can let our worries drop away. But Pulse Entertainment wanted to do things a little differently when they developed Bad Mojo in 1996. They wanted to put the player in the little brown shell of a cockroach. You play as Roger Samms, who…

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