Drs. Spencer and Karl Nadolsky talk about nutrition, medicine, and fitness through the lens of two physicians who lift weights. Both doctors are former NCAA division 1 wrestlers who have gone into medicine. Dr. Spencer Nadolsky is a board certified family physician specialized in obesity medicine and lipidology. Dr. Karl Nadolsky is a board certified endocrinologist also specialized in obesity medicine.
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1st longer term tirzepatide study (3 years)
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Drs. Karl and Spencer discuss the brand new 3 year study of tirzepatide in those with prediabetes along with a discussion on semaglutide treating osteoarthritis. Learn: If people lose weight and keep it off with tirzepatide How many people regain weight after stopping the medicine Long-term side effects If semaglutide helps with osteoarthritis Clic…
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Making America Healthy Again - Joe Rogan Podcast Review
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53:12
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53:12
Drs. Karl and Spencer invite Dr. Andrea Love back to the podcast to discuss a recent Joe Rogan podcast with Calley and Casey Means along with the concept of Make America Healthy Again and RFK jr. Learn: What the docs agree with. What they don't agree with. Is raw milk okay? Are cancer rates rising? and more Follow Dr. Andrea here https://www.instag…
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Drs. Karl and Spencer discuss all things cortisol and poke fun at the influencers who try to fear monger exercise due to cortisol increases. Learn: What is cortisol and what does it do? Is cortisol bad? Should you worry about cortisol increases with exercise? Should you take supplements to lower cortisol? and more…
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New Healthcare Service
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22:05
Drs. Karl and Spencer discuss their ideal healthcare delivery system. Learn: Spencer's journey building and selling Sequence and what he wants to do next. How Dr. Karl believes healthcare should be and what he's doing next. Click here to get on Dr. Spencer's waitlistDocs Who Lift
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Obesity medicine updates and Kardashian supplements
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40:13
Drs. Karl and Spencer discuss BS supplements claiming to be like Ozempic along with discuss some new obesity drugs coming down the pipeline that were announced in phase 1 and 2 trials. Are there any supplements that can mimic Ozempic? What is amylin and how does it help with weight and sugars? What is this new oral drug "amycretin" in phase 1 trial…
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Drs. Karl and Spencer chat with Dr. Jen Gunter all about menopause. Learn: How it's diagnosed. When and when not to treat. The various treatment. If it is indicated for cardiovascular disease prevention or body composition. Whether or not you should get labs. See more at Dr. Gunter's websiteDocs Who Lift
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Olympic controversies and GLP-1 for Alzheimer's and Heart Failure
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27:26
Drs. Karl and Spencer talk about the top line results from study showing liraglutide may have some benefit in Alzheimer's along with top line results from the Summit trial showing heart failure benefits with tirzepatide. They also discuss the women's boxing controversy and BMI in athletes.Docs Who Lift
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New Vitamin D Guidelines
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Drs. Karl and Spencer chat with return guest and bone expert endocrinologist Dr. Rachel Pessah-Pollack all about the new Vitamin D guidelines. Should healthy people even check a vitamin D level? Should they supplement with vitamin D? What people should check or supplement? Click here for the new guidelines…
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Semaglutide and Blindness
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51:02
Does semaglutide cause blindness? What is NAION (nonarteritic anterio ischemic optic neuropathy)? What about worsening of diabetic retinopathy with semaglutide? What can you do to minimize the risk of NAION and retinopathy? Get the full study here Read Dr. Brugger's blogDocs Who Lift
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Tirzepatide for Obstructive Sleep Apnea
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Tirzepatide may be a good option if you have obesity and obstructive sleep apnea. Click here to read the studyDocs Who Lift
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Stomach Ablation for Weight Loss
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34:18
Click here to read about the gastric ablation and trial. Click here to see Dr. McGowan's clinicDocs Who Lift
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FLOW trial and GLP-1 cost rant
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45:30
Drs. Karl and Spencer discuss the recent FLOW trial where semaglutide was found to be kidney protective. They also go off about the costs of these medicines and what to do (including compounding considerations). Click here to see the studyDocs Who Lift
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South Park - The End of Obesity
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Drs. Karl and Spencer discuss the most recent South Park episode where GLP-1 medicines are discussed along with the dysfunctions of our healthcare system among other issues.Docs Who Lift
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Fallacies of Functional Medicine
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Drs. Karl and Spencer discuss the fallacies of functional medicine. You'll learn what functional medicine is and whether you should seek it out.Docs Who Lift
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Another response to Jillian Michaels and Bill Maher
20:24
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Drs. Karl and Spencer respond to Jillian Michaels on the Bill Maher showDocs Who Lift
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Bariatric surgery through the mouth? Endoscopy gastroplasty 101
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Drs. Karl and Spencer discuss with gastroenterologist Dr. McGowan all about endoscopic gastroplasty. See recent study on cost effectiveness of endoscopic gastroplasty vs semaglutide Check out his programDocs Who Lift
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GLP-1 meds and Parkinson's and Heart Failure
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Drs. Karl and Spencer discuss the new studies about GLP-1 medicines and Parkinson's and heart failure along with how these meds are not just weight loss drugs but health promoting medicines. Click here to see the Parkinson's study Click here to see the heart failure studyDocs Who Lift
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Lipedema Patient Journey
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Drs. Karl and Spencer chat with Kasey Potts all about her journey with lipedema. Learn more about how this condition is diagnosed and treated. Check out her instagramDocs Who Lift
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All about Lipedema - with Dr. Amron
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Drs. Karl and Spencer chat with Dr. Amron all about lipedema. He is a specialized surgeon who treats lipedema daily. Learn about diagnosing and treating this condition that is commonly mistaken with obesity. Check his sites https://www.dramronconsultations.com/ https://www.advancedlipedematreatment.com/…
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GLP-1 Weight Loss Maintenance from Exercise
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Drs. Karl and Spencer discuss a new study showcasing the importance of exercise during and after GLP-1 medicine use. Click here to see the original study Click here to see the extension studyDocs Who Lift
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Bustin' Hyman Myths - GLP-1 edition
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Drs. Karl and Spencer discuss a recent Mark Hyman podcast where he perpetuated some myths about obesity and GLP-1 receptor agonist medicines.Docs Who Lift
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Does your doctor need to be in shape?
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Drs. Karl and Spencer discuss whether your doctor needs to look a certain way in order to be a good doctor.Docs Who Lift
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Docs Who Lift and Unbiased Science Crossover
1:16:03
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Drs. Karl and Spencer chat with Drs. Jess and Andrea all about popular podcasters like Andrew Huberman etc. and the spread of pseudoscience.Docs Who Lift
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The death of our supplement company and influencer pharma money
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Drs. Karl and Spencer chat about their now defunct supplement company along with the ethics of big pharma direct to consumer marketing (including influencers).Docs Who Lift
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Drs. Karl and Spencer chat with Dr. Brianna Durand all about the pelvic floor and incontinence when lifting etc. empower.physio pelvicrehab.orgDocs Who Lift
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How much protein should you eat? W/ Dr. Stu Phillips
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Drs. Karl and Spencer chat with Dr. Stuart Phillips all about protein. How much do you need to eat for optimal health and body composition and more!Docs Who Lift
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CGMs for those without type 2 diabetes w/ Dr. Nicola Guess
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Drs. Karl and Spencer chat with Dr. Nicola Guess all about the evidence behind using continuous glucose monitors in those without type 2 diabetes. Learn whether they are useful for even harmful Read her review paper hereDocs Who Lift
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SELECT results - Wegovy reduces heart attacks
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Drs. Karl and Spencer discuss the new SELECT results that show a decrease in cardiovascular events in those taking Wegovy who have a history of cardiovascular disease. See trial below https://www.nejm.org/doi/full/10.1056/NEJMoa2307563Docs Who Lift
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Zepbound - Tirzepatide for obesity approval
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Drs. Karl and Spencer discuss how tirzepatide is now approved for obesity. Learn: When will it be available How much will is cost Any differences compared to Mounjaro Surmount 3 trialDocs Who Lift
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Brain changes and obesity
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Drs. Karl and Spencer chat with Dr. Kathleen Keller and Yash Adroja all about brain signaling in kids in relation to obesity. Learn all about Dr. Keller's research that sheds light on taste preferences and food choices made by kids.Docs Who Lift
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Tirzepatide updates from EASD
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Drs. Karl and Spencer chat about some of the new tirzepatide studies including SURMOUNT-4 from the EASDDocs Who Lift
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Exercise for type 2 diabetes
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Drs. Karl and Spencer discuss with Dr. Bassin all about her review on exercise and physical activity for type 2 diabetes. Check out her review articleDocs Who Lift
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GLP-1 Agonists and Heart Health
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Drs. Karl and Spencer discuss how semaglutide impacts the heart with new trial data available. Learn how semaglutide may reduce risks of heart attacks and also how it impacts your quality of life if you have heart failure.Docs Who Lift
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All about the Microbiome
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28:58
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Drs. Karl and Spencer chat with Dr. Andrea Love all about the microbiome. Find out if it really matters and if there are things to improve it.Docs Who Lift
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Eating Disorder Diaries
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Drs. Karl and Spencer chat with Amy Goekel about her history of her eating disorder. Amy has her own podcast where she discusses it is more depth as well https://podcasts.apple.com/us/podcast/the-eating-disorder-diaries/id1666122772Docs Who Lift
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Diet Soda, Cancer, and the WHO
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Drs. Karl and Spencer chat with Dr. Andrea Love, a cancer immunologist, about the recent headlines about the WHO listing aspartame as a possible carcinogen.Docs Who Lift
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Internalized bias and what to do about it with Dr. Rebecca Pearl
36:27
36:27
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Drs. Karl and Spencer chat with Dr. Pearl all about internalized bias and her recent study on it Click here to read the studyDocs Who Lift
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Another genetic cause of obesity - Bardet Biedl Syndrome
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56:27
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Drs. Karl and Spencer chat with Dr. Jesse Richards all about BBS (Bardet Biedl Syndrome), an unknown cause of genetic obesity.Docs Who Lift
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The WHO and artificial sweeteners
31:17
31:17
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31:17
Drs. Karl and Spencer sit with Dr. Nagra to discuss the recent WHO news headlines about artificial sweeteners. Find out why you should still drink diet soda instead of regular soda.Docs Who Lift
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A chat with Dr. Salas-Whalen
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35:18
Drs. Karl and Spencer chat with Dr. Salas-Whalen, an endocrinologist, about getting the appropriate clinician to prescribe you GLP-1 medicines.Docs Who Lift
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Supplements for cholesterol and saunas for living longer
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Drs. Karl and Spencer discuss with cardiologist Dr. Luke Laffin about his recent study looking at statins versus various supplements touted as cholesterol-lowering. We also discuss the claim about saunas being better than drugs at lowering mortality.Docs Who Lift
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Chatting with the Obesity Medicine Association president
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46:43
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46:43
Drs. Karl and Spencer chat with Dr. Angela Fitch, the president of the Obesity Medicine Association and a fellow doc who lifts! They discuss Dr. Fitch's journey into lifting along with the importance of body composition in obesity management. Dr. Fitch is also the CMO of her new company KnownWell. Need an online workout program? Check out LiftRx…
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GLP-1 agonists and lean body mass loss part 2 w/ Dr. Grant Tinsley
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Drs. Karl and Spencer bring back Dr. Grant Tinsley, a body composition researcher, to go over the GLP-1 data (semaglutide and tirzepatide) in terms of lean body mass loss. Learn: - How much lean body mass is lost in these trials - How body composition is measured - How is muscle loss assessed - Should you be worried if you're taking a GLP-1 agonist…
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Food, exercise, and lifestyle as medicine?
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Drs. Karl and Spencer discuss whether we should call lifestyle measures "medicine".Docs Who Lift
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Intro to SGLT2 inhibitors - just pee out calories
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Drs. Karl and Spencer discuss the drugs that help you pee out calories - SGLT2 inhibitors. Learn how this type 2 diabetes medicine has turned into a great drug for other conditions.Docs Who Lift
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The myths of GLP-1 agonists
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Drs. Karl and Spencer go over the common myths of the GLP-1 agonists. Is Ozempic face real? Do people get pancreatic cancer or pancreatitis? Find out by listening!Docs Who Lift
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Obesity Medicine and Insurance Woes
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Drs. Karl and Spencer chat with Dr. Leslie Golden about the troubles with insurance covering obesity medicine.Docs Who Lift
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Erythritol and Cardiovascular Disease
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Drs. Karl and Spencer sit down with Dr. Nicola Guess, an RD PhD scientist, to discuss the new alarming study regarding erythritol. Read the review that goes over the endogenous vs exogenous erythritolDocs Who Lift
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GLP-1s and Lean Mass Loss
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25:19
Drs. Karl and Spencer discuss the worry surrounding lean mass loss while using GLP-1 agonists. Learn: - The usual amount of lean mass loss during weight loss - How much was lost in small subset using semaglutide and tirzepatide - What is the clinical relevance - and more!Docs Who Lift
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Drs. Karl and Spencer discuss the phenomena of those who believe cholesterol (and lipoproteins that carry cholesterol) doesn't cause heart disease. Learn: - How Dr. Spencer was also a skeptic when first starting medical school - How the data are pretty overwhelming for cholesterol/apoB/LDL particles causing heart disease…
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