Episode 131 - Vivian Li - “I felt like the intestine is actually quite a beautiful system.”

StemCells@Lunch Digested

#Stem Cell #Podcasting Education #StemCellsLunch Digested Keeping

1:14:43

Artificial intelligence is evolving at an unprecedented pace—what does that mean for the future of technology, venture capital, business, and even our understanding of ourselves? Award-winning journalist and writer Anil Ananthaswamy joins us for our latest episode to discuss his latest book Why Machines Learn: The Elegant Math Behind Modern AI . Anil helps us explore the journey and many breakthroughs that have propelled machine learning from simple perceptrons to the sophisticated algorithms shaping today’s AI revolution, powering GPT and other models. The discussion aims to demystify some of the underlying mathematical concepts that power modern machine learning, to help everyone grasp this technology impacting our lives–even if your last math class was in high school. Anil walks us through the power of scaling laws, the shift from training to inference optimization, and the debate among AI’s pioneers about the road to AGI—should we be concerned, or are we still missing key pieces of the puzzle? The conversation also delves into AI’s philosophical implications—could understanding how machines learn help us better understand ourselves? And what challenges remain before AI systems can truly operate with agency? If you enjoy this episode, please subscribe and leave us a review on your favorite podcast platform. Sign up for our newsletter at techsurgepodcast.com for exclusive insights and updates on upcoming TechSurge Live Summits. Links: Read Why Machines Learn, Anil’s latest book on the math behind AI https://www.amazon.com/Why-Machines-Learn-Elegant-Behind/dp/0593185749 Learn more about Anil Ananthaswamy’s work and writing https://anilananthaswamy.com/ Watch Anil Ananthaswamy’s TED Talk on AI and intelligence https://www.ted.com/speakers/anil_ananthaswamy Discover the MIT Knight Science Journalism Fellowship that shaped Anil’s AI research https://ksj.mit.edu/ Understand the Perceptron, the foundation of neural networks https://en.wikipedia.org/wiki/Perceptron Read about the Perceptron Convergence Theorem and its significance https://www.nature.com/articles/323533a0…

4 года назад 18:38

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On today’s episode, Dr Vivian Li, group leader of the Stem Cell and Cancer Laboratory at the Francis Crick Institute, is interviewed by PhD student Elena Drudi. Vivian talks about her background in plant biotechnology, colon cancer research and working in Hans Clevers lab and her current research focus using human gut organoids to ask how stem cells are maintained in healthy guts, what happens when it goes wrong, and the Wnt signalling pathway’s role in this. She also talks about the future of engineering parts of the bowel to replace damaged and missing bowel. For more information on Vivian’s work check out the following link: https://www.crick.ac.uk/research/labs/vivian-li

156 эпизодов

Episode 131 - Vivian Li - “I felt like the intestine is actually quite a beautiful system.”

StemCells@Lunch Digested

published 4 года назад

MP3•Главная эпизода

156 эпизодов

#Stem Cell #Podcasting Education #StemCellsLunch Digested Keeping

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Episode 153: Dr Ina Sonnen "It is possible to have a career and a family in science" 24:43

2 years назад24:43

24:43

In this episode, Ina Sonnen, a researcher at the Hubrecht Institute in the Netherlands, is interviewed by Postdocoral researcher JF Darrigrand. Ina explains which are the big questions studied in her lab, notably how cells can communicate not only via the nature of signals they exchange but also through the dynamics of these signlas. She shares how advances in microscopy, microfluidics and cell culture are helping researchers to make more and more discoveries. Having recently founded her lab, she tells us more about what she found was either challenging or rewarding in her new role. Lastly, she insists on why she thinks being a scientist is a good job when you want to start a family. To find out more about Ina's research, check out the following links: https://www.sonnenlab.org…

StemCells@Lunch Digested

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Episode 152: Prof Andrew Ewald "Understand the simple rules generating apparent complexity" 23:34

3 years назад23:34

23:34

In today’s episode, Prof. Andrew Ewald, Director of the Cell Biology Department at the Johns Hopkins School of Medicine is interviewed by Inês Tomás. Prof Ewald explains how he transitionned from a background in physics to the field of cancer biology. He touches upon why cancer is such a specific type of disease, how cancer cells talk to each other during metastasis, and how their interaction with immune cells is crucial for disease development. Prof Ewald also discusses the evolution of the tools available for cancer biologists and how the emergence of new technologies are changing the field. Lastly, he shares some inspiring mentoring advice on how to reach an interdisciplinary and rewarding career.…

StemCells@Lunch Digested

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Episode 151: Dr William Roman "Use your PhD as a platform" 16:38

3 years назад16:38

16:38

In today’s episode, Dr. William Roman, a research associate at Stanford University, is interviewed by Dr. Davide Danovi. William explains how he is combining live cell imaging and quantitative approaches to answer fundamental questions in muscle biology. He shares some inspiring mentoring advice on how to let students use their PhDs as platforms to express themselves throught their science and discover what type of science they like, both in terms of subject and technique.…

StemCells@Lunch Digested

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Episode 150: Prof Shalev Itzkovitz "We can infer the design principles of organs" 29:23

3 years назад29:23

29:23

In today’s episode, Shalev Itzkovitz, a professor at the Weizman Institute, Israel, is interviewed by Postdocoral researcher Georgina Goss. Shalev shares the discoveries of his lab on the design principles that shape and maintain metabolic organs such as the intestine and the liver. He explains the very advanced techniques used in modern biology, and more specifically in his lab, to address such fundamental questions. Having started his education in mechanical engineering, he discusses what motivated him to transition to the resolution of biological questions and how resolving these questions is somewhat similar to retro-engineering. Lastly, he touches upon what fascinates him in studying the biology of metabolic organs. To find out more about Shalev's research, check out the following links: https://shalevlab.weizmann.ac.il…

StemCells@Lunch Digested

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Episode 149: Professor Xin Chen-“We are very fascinated by this kind of ‘immortality’ of germ cells” 15:53

3 years назад15:53

15:53

In today’s episode, Prof Xin Chen, a group leader at Johns Hopkins University in Baltimore, is interviewed by PhD student Daria Belokhvostova. Xin takes us into the world of germline stem cell epigenetics and how its regulation can influence the ability of these cells to divide asymmetrically. She shares her passion for the biology of germ cells and explains why the fruit fly Drosophila is such a good system for her studies. Xin talks about how scientific collaborations are helping to expand her findings to different biological systems. Finally, she tells us about the challenges of keeping the lab running through pandemic times and the joy of seeing in-person interactions come back. To find out more about Xin’s research, check out the following link: https://bio.jhu.edu/directory/xin-chen/…

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Episode 148: Dr Allison Bardin- “Unexpected results lead to novel discoveries” 15:57

3 years назад15:57

15:57

In today’s episode, Dr Allison Bardin, a group leader at Institut Curie, is interviewed by PhD student Vassia Salameti. Allison talks about how she got interested in asymmetric cell division while working on budding yeast, followed by her work on fly as a postdoc that derived her into the field to study cell fate acquisitions and stem cell biology. She shared the details about how Drosophila is excellent model to study various genetic alterations and cost effective. Allison further emphasised on the importance of fundamental research and how that could lead to interesting discoveries that could be further translated into clinics. Finally, she talks about importance of collaboration as well as importing expertise in lab along with some interesting advice for PhDs who plan to pursue academic career. To find out more about Allison's research, check out the following link: https://science.institut-curie.org/research/biology-cancer-genetics-and-epigenetics/developmental-biology-and-genetics/team-bardin/…

StemCells@Lunch Digested

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Episode 147: Professor Yukiko Yamashita- “Junk DNA may not be all Junk” 16:27

3 years назад16:27

16:27

In today’s episode, Prof Yukiko Yamashita, a group leader at Whitehead Institute for Biomedical Research, MIT, is interviewed by PhD student Joshua Reeves. Yukiko talks about how her lab got interested in understanding the possible mechanism of non siter chromatid segregation in germline cells. She talks about how they started looking at the interesting mechanisms regulating the immortality of germlines cells in Drosophila. Yukiko also shares her opinion regarding Junk DNA and how it might not all be junk like noncoding RNAs. Lastly, she shares her advice to be learner for rest of life and get used to stepping outside comfort zone. And to become comfortable not being expert all the time. To find out more about Yukiko’s research, check out the following link: https://yamashitalab.wi.mit.edu/…

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Episode 146: Prof Ludo Van Den Bosch– “Exciting time for researchers” 14:32

3 years назад14:32

14:32

In today’s episode, Prof Ludo Van Den Bosch a group leader at VIB-KU Leuven Center for Brain & Disease Research, is interviewed by PhD student Abigail Isaacson. Ludo talks about his labs goal and how they use different model systems to understand disease as good as possible with goal to develop therapies. He also highlighted the importance of using different models from fruit fly, zebrafish to mice depending on context and questions. Ludo also emphasized about obstacles in managing ALS along with advancement in past 25yrs and how iPSCs have made big difference and given new insights for understanding diseases. Ludo shared his experience as being a scientist and how much he enjoy interaction with young people and other fellow colleagues. To find out more about Ludo's research, check out the following link: https://cbd.vib.be/labs/van-den-bosch-lab…

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Episode 145: Prof Elena Ezhkova- “The more you try understand science the more interesting it gets” 15:39

3 years назад15:39

15:39

In today’s episode, Prof Elena Ezhkova, a group leader at Icahn School of Medicine, is interviewed by PhD student Vassia Salameti. Elena talks about the potential of stem cells in therapy and how her interest developed towards understanding the role of epigenetic regulators in stem cell reprogramming. She shares about how companies are getting interested in small molecular drugs that target epigenetic regulators which could be used as personalized therapy. Elena also emphasizes the importance of clinical collaboration and highlights how important it is to get the inputs from clinicians at the beginning of project to get better understanding of the disease. Lastly, she shares her advice for PhDs to find the research direction of interest and not be afraid things will work out!!! To find out more about Elena's research, check out the following link: https://www.ezhkova-lab.com/…

StemCells@Lunch Digested

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Episode 144- Prof Filipe Pereira- "It's about defining what will keep you fueled for years" 19:07

3 years назад19:07

19:07

In today’s episode, Prof Filipe Pereira, a professor at Lund University, Sweden, is interviewed by postdocoral researcher Jean-Francois Darrigrand. Filipe shares how he started his career in the fields of stem cells reprogramming and immunotherapy, as well as his experience working in the US and different european countries. Filipe also discusses about how he balances his activities of leader of an academic group and of a biotech company. Lastly, he explains why mentoring is a fantastic source of motivation for him. To find out more about Filipe's research, check out the following link: https://pereiralab.com/team/carlos-filipe-pereira/…

StemCells@Lunch Digested

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Episode 143 -Prof Denis Duboule - "As long as people are happy in your lab, it's fine" 14:38

3 years назад14:38

14:38

In today’s episode, Prof Denis Duboule, a professor of developmental biology at EPFL and Univeristy of Geneva is interviewed by PhD student Abigail Isaacson. Denis talks about how his first interest for mushrooms initiated his whole career in biology. He shares with us his fascination for the encoding of time in the genome, which ensures the proper development of embryos. Denis also talks about how priotities change during the life of a laboratory head, shifting from publishing to seeing your lab members grow and succeed on their own. To find out more about Denis' research, check out the following link: https://genev.unige.ch/research/laboratory/Denis-Duboule…

StemCells@Lunch Digested

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Episode 142 -Prof Dagmar Iber- "Don't play too safe and be lucky." 11:05

4 years назад11:05

11:05

In today’s episode, Prof Dagmar Iber, a professor at ETH, Zurich, is interviewed by PhD student Vasiliki Salameti. Dagmar talks about the similarity between investment banking and academia . She describes her interest in modelling organogenesis and patterning systems. She discusses the importance of collaboration. She also advised students to take risk and initiative to try to do things they want to. As a university professor, she shared how she enjoyed the scientific journey in finding things out, but also teaching and seeing students grow. To find out more about Dagmar's research, check out the following links: https://www.bsse.ethz.ch/cobi https://bsse.ethz.ch/cobi/group/people/person-detail.MTQ5NDI0.TGlzdC8yMjA0LC0xMDM3ODQxNDk3.html…

StemCells@Lunch Digested

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Episode 141 - Dr Vikas Trivedi - “You get to learn things from people that you would not know” 18:47

4 years назад18:47

18:47

In today’s episode, Dr Vikas Trivedi, a group leader at EMBL Barcelona, is interviewed by PhD student Prudence Lui. Vikas talks about his scientific journey and his research on using embryonic organoids to study self-organisation of cells. He describes the challenge in this field to use interdisciplinary approaches to study complex biological phenomena. He discusses the benefits of developing broad multidisciplinary expertise at the lab. As a group leader in science, he finds problem solving, working with intelligent people and contributing to other people’s career very rewarding. We also get to learn about Vikas’s interests beyond the lab. To find out more about Vikas's research, check out the following link: https://www.embl.org/groups/trivedi/…

StemCells@Lunch Digested

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Episode 140- Dr Emma Rawlins "I'll look at stem cell in any systems" 21:49

4 years назад21:49

21:49

In today’s episode, Dr Emma Rawlins, a senior group leader at the Gurdon Institute in University of Cambridge. She is interviewed by PhD student Elena Drudi. Emma talks about her research on stem cells in mammalian lungs using both mouse and human organoid models. She discusses the pros and cons of the two models. She describes her research interest in understanding normal embryonic lung development, with the aim to further repurpose these cues for lung repair/regeneration in adults. She emphasises how functional human genetics on a population level, in combination with human organoids models, can further help dissecting diseases susceptibility and regeneration. She also shares her journey from studying drosophila to human lung biology, and how going aboard no longer seems to be a necessity to continue one's career. To learn more about Emma’s recent postdoc work, check out the following links: https://www.gurdon.cam.ac.uk/research/rawlins…

StemCells@Lunch Digested

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Episode 139 - Dr Vanessa Ribes - “We make bonds in thinking and developing ideas” 18:49

4 years назад18:49