Analytical Chemistry is a peer-reviewed research journal that explores the latest concepts in analytical measurements and the best new ways to increase accuracy, selectivity, sensitivity, and reproducibility.
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Chemistry is of enormous importance in everyday life: almost everything that exists, and all that we see, make and eat is composed of molecules. The unravelling of molecular structure is a key activity of chemists. In these three video tracks, Dr Mike Bullivant looks briefly at three of the spectroscopic techniques that are used to determine the structure of chemical compounds - infrared spectroscopy, proton (1H) and 13C nuclear magnetic resonance (nmr) spectroscopy, and mass spectrometry. T ...
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It’s almost impossible to overstate how many aspects of daily life are impacted by science. From technologies that help ensure the quality of the water we drink, to medicines that deliver lifesaving treatments – it’s all thanks to science. Each month, members of Thermo Fisher Scientific's team talk to experts who are on the cutting-edge of redefining how we exist. This is Science with a Twist.
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Did you know that one of the most important public health programs, one that impacts the lives of our newborn babies, is largely unknown to the public at-large? The practice of screening all newborn babies at birth, for metabolic and a variety of other disorders, is something that most parents probably don’t ever think about, nor do they usually receive the test results. Why do advancements in newborn screening, that affect the health and well-being of our children, seem to be a mystery to s ...
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Enabling Healthier Communities: Thermo Fisher's Impact
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Listen to the conversation as they discuss: How health equity is a key component of Thermo Fisher’s core business. How Thermo Fisher leverages its capabilities and customer relationships to further its impact. Initiatives that improve health equity through accessibility to drug-resistant HIV testing, next-generation sequencing to diagnose lung and …
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Access to Clinical Trials: Eliminating Barriers to Enrollment for Women
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Dr. Blackburne shares insights into: The challenges of recruiting women and minority groups for clinical trials, noting the logistical and societal barriers they face. Innovative solutions, such as telemedicine and flexible scheduling, to make trial participation more accessible. Recent advances in clinical research, including a groundbreaking pree…
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From Waste to Worth: Rethinking Plastics with NREL's Insights
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The Critical Role of Plastics in Modern Society Despite the challenges associated with plastic in the environment, Kat Knauer, Ph.D., emphasizes the indispensable role of plastics in healthcare, research, and daily life. She points out that while plastics have significantly improved quality of life and medical care, their improper disposal poses a …
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It’s In Our Genes: The Potential of Gene Therapy with Dr. Peter Marks
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Gene Therapy's Potential to Transform Rare Disease Treatment Dr. Peter Marks highlights the groundbreaking advancements in gene therapy, especially for rare diseases with high unmet medical needs. He discusses the FDA's role in fostering these innovations, underscoring the importance of understanding gene therapy's application and ensuring its safe…
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Decoding Cellular Secrets: Advances in Mass Spectrometry Technology
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Revolutionizing Biomedical Research with Mass Spectrometry Joshua J. Coon discusses the transformative role of mass spectrometry in biomedical research. This technology, as he explains, allows for the precise weighing of molecules, providing critical insights into their identity and quantity. Coon's lab utilizes mass spectrometry to analyze complex…
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Tackling HIV Drug Resistance: Brazil's Approach and Global Implications
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Brazil's Proactive Measures Against HIV Brazil has been at the forefront of combating HIV, implementing proactive measures that have made a significant difference. The country began providing no-cost access to CD4 and viral load testing and antiretroviral drugs as early as 1996. This early intervention and consistent approach led to a remarkable ou…
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Powering Everyday Life: The significance and impacts of the semiconductor industry
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⚡Semiconductor chips go through a long manufacturing process. It all depends on the type of chip, but the standard timeframe is between 120 days and nine months. It is a three-phase process that includes design and frontend and backend manufacturing, all dependent on various factors. ''These are global supply chains supporting the completed product…
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Shaping the Future through STEM Education: The importance of access and equity
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The Power of Passion in STEM Eleanor emphasizes the importance of pursuing what you love in STEM. She advises students to focus on their interests rather than trying to impress judges or make a big impact. Eleanor encourages students to be scrappy and innovative and to believe in their ability to navigate through challenges. She underscores that ST…
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Pharmacogenomics: A New Era of Patient-Centric Care
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The Power of Pharmacogenomics Jeff explains how pharmacogenomics, the study of how genes affect a person's response to medications, can revolutionize healthcare. By understanding a patient's genetic makeup, healthcare providers can prescribe the right medication and dosage, reducing trial and error, improving treatment effectiveness, and minimizing…
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Forever Chemicals: The effects of PFAS and how to protect against it
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⚡PFAS stands for Per- and Polyfluoroalkyl Substances. Simply put, PFAS are man-made compounds synthesized in a laboratory. ''They were first made in the 1940s. Teflon was one of the very first developments of PFAS. PFAS is a universe of chemicals useful for lots of different consumer and industrial applications over the last 60 to 70 years. These i…
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Green Chemistry: Designing for a Sustainable Future
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⚡ Green chemistry aims to anticipate toxicity and global climate change. Green chemistry is an area of chemistry that focuses on reducing pollution and building a more sustainable world. John explains, "What you may be surprised to learn is that if you look at the curriculum, if you look at the classes that a chemist takes from the very beginning t…
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Delivering on the promise of cell therapies: Programmed immune cells attack cancer and other diseases
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⚡ Cell therapy is a promising field. Cell therapies can potentially transform medicine and treat some of the most severe diseases, like cancer. Wendell says, "That's one of the innate challenges here — how do you make something that's very controlled and specific and yet also very potent enough to really overcome the disease. And that's where we re…
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Disrupting the Status Quo: The Importance of Diversity in Clinical Trials
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⚡ What are the ramifications from a clinical research perspective if diversity is not appropriately represented in a clinical study populations? Even as diversity becomes increasingly important across different sectors, minorities continue to be left out of clinical trials and medical research studies. So, why is diversity so critical in clinical t…
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Putting Patients First: The Benefits of Decentralized Clinical Trials
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⚡ Decentralized clinical trials aim to reduce patient burden. Decentralized clinical trials can help make research more patient-centric. Tim explains the role of decentralization, "It's fair to say that that change management component is absolutely critical in terms of the decentralized adoption, and I think, when I look ahead in terms of decentra…
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No One Missed: Empowering Lung Cancer Patients with Biomarker Insights
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⚡ There's a diversity mismatch in the oncology workforce. One of the biggest challenges in the oncology space is a lack of diversity in the workforce. The population of the United States is very diverse, while the oncology field is not. Dr. Upal Basu Roy says, "We know that the United States is very diverse. As we speak, the population is very dive…
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Saved Time Saves Lives: The Impact of Rapid Turnaround Time for Cancer Patients
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⚡The most critical part is to shorten the time between doing the test and getting the results. From there, doctors will be better positioned to provide the best care to the patient. ''There's always pressure from the patient, the family, and the physician to start therapy as soon as possible. [...] So getting that test earlier allows us to do the r…
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One Health: How human, environmental, and animal health intersect
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⚡ We can't limit ourselves to only humans and animals to fight diseases and cure illnesses. To cure diseases and illnesses, we need to understand how the environment, humans, and animals intersect. Professor Akebe explains, "We get that whole cycle that starts again. It [waste] leaves from our homes. It leaves from our hospitals. It gets into the t…
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Behind the MoonArk: How a Team of Artists Embraced Science to Send a Time Capsule to the Moon
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⚡ The MoonArk is both conceptual art and a time capsule. Almost 15 years ago, the idea was to create a time capsule carrying fragments of the world as we know it today and send it to the moon to be discovered in the distant future. Today, the project has 60 members from 18 institutions and over 250 contributing designers, scientists, poets, musicia…
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Uncovering the Past: How Jewish Holocaust victims were discovered at a death camp in Sobibór
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💡 DNA analysis enables the identification of missing persons. Asked about the impact of DNA analysis, Dr. Diepenbroek explains that such a method helps identify the victims regardless of time passed. Forensics uses the DNA from unknown remains and matches them with the DNA of missing persons’ relatives. Alongside her colleagues — including experts …
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Virus Variants Explained: Why COVID-19 Variants Arise
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🎙 What are virus mutations, and what do they mean? Just like other viruses, COVID mutates all the time. Andy explains what mutation is, how it happens, and the importance of monitoring it. "What we need to capture in these surveillance efforts is how these viruses are changing and how quickly they are changing. So you've heard of mutations, and the…
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COVID In the Air? How a new in-air pathogen surveillance solution was used in some Wisconsin schools to detect airborne coronavirus particles
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🎙️ The AerosolSense Sampler is an in-air pathogen monitoring solution. Miguel introduced the AerosolSense Sampler, a new technology that can be used in conjunction with other risk mitigation tools (masks, vaccines, testing) in the fight against COVID-19. It is designed to detect the presence of coronavirus and other airborne pathogens in the air in…
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Was mass spectrometry the right technique to screen large populations?
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No one really knew whether mass spectrometry was up to the task of population screening. Could the instruments cope with the tens-of-thousands of dried blood spots that needed to be analyzed every year? In the mid 1990s, Dr. Mike Morris began working with newborn screening labs around the world to try and answer these questions.…
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Patient Perspectives: CAR-T Cell Therapy
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On this episode of Science With a Twist, Ron O’Brien interviews Matthew Moon, a CAR-T cell therapy recipient who was able to beat leukemia thanks to the advances in the field. Matthew and Ron discuss the timeline of health-related events that led to Matthew’s diagnosis and his unique journey to find a life-saving cell therapy clinical trial. After …
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The application of tandem mass spectrometry to NBS for amino acids and acylcarnitines - An interview with David Millington
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For the 30 years following Dr. Robert Guthrie's invention of a PKU screening test newborn screening tests were limited in number. That all changed when biochemists at Duke University first applied tandem mass spectrometry to solve a puzzling clinical case. The result changed the way the newborn screening community thought about adding new screening…
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Sustainability: What is it and why should we care?
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On this special Earth-Day episode of Science With a Twist, Ron O’Brien speaks with Emelia DeForce, Field Applications Scientist for Laboratory Plastics & Essentials at Thermo Fisher Scientific. Emelia and Ron chat about sustainability, what it means, and why we should all care about it.Thermo Fisher
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COVID-19: Why We Need to Continue Testing
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Manoj Gandhi, Sr. Medical Director at Thermo Fisher Scientific, interviews Dr. Stephen Morse, professor of epidemiology at Columbia University. Manoj and Stephen address the doubts expressed by the general public regarding testing for COVID-19 and the need for continued testing even as vaccination rates continue to increase.…
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Let's start from the start: A review of Dr. Robert Guthrie's 1963 paper on PKU screening
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It all started with a pediatrician's desire to save newborn babies from a rare but devasting metabolic disorder. But, Dr. Robert Guthrie's elegantly simple screening test for PKU (phenylketonuria) started a movement that has improved or saved the lives of countless newborn babies around the world.Waters Corporation
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Breath Biopsy: Non-invasive analysis of biomarkers in early detection and precision medicine
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Billy Boyle, CEO of Owlstone Medical, sits down with Ron O'Brien to talk about breath biopsy. This technology provides an entirely new way to access this information by collecting and analyzing breath samples.Thermo Fisher
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Trailer for the Renata Newborn Screening Podcast.Waters Corporation
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The Just Project: Facilitating the Safe Reopening of HBCUs
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Social and economic inequality has made minority communities more prone to contracting SARS-COV-2; the virus that causes COVID-19. One of those severely affected is the black community in the United States. On this episode of Science With a Twist, Fred Lowery, Senior Vice President and President of Life Sciences Solutions and Laboratory Products at…
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Twindemic: How the Seasonal Flu Collides with the COVID-19 Pandemic
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Ron O'Brien speaks with Dr. Stephen Young, an expert in Microbiology, with a background in pathology, virology, and infectious diseases. They discuss what we should know during the potential viral storm produced by the collision of the seasonal flu and the COVID-19 pandemic.Thermo Fisher
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Paolo Braiuca interviews Dr. Frank Leibfarth from the University of North Carolina at Chapel Hill. Frank talks about his group's exciting work in polymer chemistry as well as topics related to his collegiate football career and the challenges of managing an academic lab in the era of COVID-19.Thermo Fisher
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Chemistry of Human Milk
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On this episode of Science With a Twist, Paolo Braiuca interviews Dr. Steven Townsend. Through his research, Steven is trying to demystify the science of human milk. His work on human milk oligosaccharides, carbohydrates whose molecules are composed of a relatively small number of monosaccharide units, won him the consideration for the American Che…
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COVID-19: Insights on Vaccine Development
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Ron O’Brien speaks with Mary Kay Bates, Senior Cell Culture Scientist at Thermo Fisher Scientific. Mary gives us an inside look into the complex world of vaccine development and why developing one for COVID-19 has been so different. You can listen here or on your favorite podcast platform.Thermo Fisher
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World Water Day: The importance of (clean) water and conservation
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Water is everywhere, but accessible drinking water is not. In celebration of World Water Day (March 22), we’re tackling the importance of water preservation and why improving global access to clean water matters now.Thermo Fisher
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Seeding Labs: Empowering Scientists Around the Globe
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21:51
Thermo Fisher
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Fighting Coronavirus: Confirming and Containing an Outbreak
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19:25
Thermo Fisher
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One Decision, Two Lives: The Power of Organ Donation
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In 2008, the bond between two friends became even closer when one of them made the life-altering decision to donate a kidney to the other. Since then, Louise Lerminiaux and Conna Jones have been on a journey to live their lives to the fullest, while telling their inspirational story and advocating for organ donation.…
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Detecting and Protecting: Technology to Help Determine if a Threat is Real
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For first responders at the local, state and federal level, coming into contact with unknown substances in the field can be a life-threatening situation. From opioid and bomb detection to identifying toxic chemicals in the environment, all pose physical and health hazards. Hear from Thermo Fisher field instrumentation experts Bill Kotowski and Eric…
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Cells Fighting Cancer: The Science Behind It
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In part II of this series, Amy Butler, vice president of cell biology at Thermo Fisher Scientific, talks with host Ron O’Brien about the science behind CAR T-cell therapy and how it uses the body’s own immune system to fight cancer.Thermo Fisher
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Prevent the Sneeze: The Science Behind Allergy Testing
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Allergies are everywhere and for some, even the smallest particle can trigger a reaction. In this episode of Science with a Twist, host Ron O’Brien sits down with Dr. Lakiea Wright, an allergy and immunology expert, to discuss the latest in allergy testing and why it’s critical to avoid a potentially dangerous reaction.…
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From ionic to iconic: The story of Nalgene
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The Nalgene water bottle has become a hydration staple for many, but did you know it was born from science? That’s right! The Nalge Company, founded in the 1949, went on to launch Nalgene Outdoor changing the face of high-quality hiking and camping essentials. Eric Hansen and Elissa McGee join host, Ron O’Brien, to discuss how the bottle we all kno…
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Welcome to Science with a Twist. Each month, join Ron O’Brien, a science enthusiast from Thermo Fisher, the world leader of serving science, as he talks to experts on the cutting-edge of redefining how we exist.Thermo Fisher
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Analytical Chemistry Podcast - December 2016
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Interview with Jared AndersonAnalytical Chemistry
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Analytical Chemistry Podcast - November 2016
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Interview with Vladimír HavlíčekAnalytical Chemistry
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Analytical Chemistry Podcast - October 2016
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Interview with Zhenglong ZhangAnalytical Chemistry
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Analytical Chemistry Podcast - September 2016
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Interview with Stephen Jacobson, Josh Baker, Dave Kysela and Yves BrunAnalytical Chemistry
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Analytical Chemistry Podcast - August 2016
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Interview with D. Dan HuhAnalytical Chemistry
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Interview with Andreu LloberaAnalytical Chemistry
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Analytical Chemistry Podcast - June 2016
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Interview with Boris MizaikoffAnalytical Chemistry
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