Healthspan. The podcast that will add years to your life, and life to your years
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Our channel provides longevity, anti-aging and health information. We interview experts in their field to get the latest information in the longevity space. You can also come to our YouTube channel for more information here https://www.youtube.com/channel/UCLFEKx_LchTLy_XwjPToJ3A
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Helping you learn science and biology that affect longevity and quality of life, so you can become more confident, intentional, and proactive about your health.
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Agingdoc Podcast (agingdoc.com) - Longevity & Healthspan from Barzilai Consulting


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Agingdoc Podcast (agingdoc.com) - Longevity & Healthspan from Barzilai Consulting
David Barzilai MD PhD
Agingdoc Podcast interviews longevity doctors and geroscientists to find and expedite healthspan and life extension for all. http://agingdoc.com (Barzilai Consulting). I serve as a concierge longevity health coach (Online calendar to book phone consults at agingdoc.com) and on X (@agingdoc1) and YouTube (http://youtube.com/@agingdoc) I provide free content away from the hype, buzz and misinformation proliferating on social media. I accept no sponsorship nor affiliate marketing. My audience i ...
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Modern Healthspan


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How To Optimize Your Exercise Routine | Prof Martin Gibala Ep3/3
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Here Dr Gibala talks how to think about exercise routines and nutrition as well as sharing his own protocol and the current work of his lab Dr Martin Gibala is a Professor at McMaster University where his research examines the effects of exercise at the molecular to whole body level in both healthy individuals and people with chronic diseases. In a…
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Agingdoc Podcast (agingdoc.com) - Longevity & Healthspan from Barzilai Consulting


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Great moments in geroscience - Joan Mannick puts on her boxing gloves! (courtesy: Hevolution Foundation) 🤯💪😎
2:36
Credit: Hevolution Foundation clip - support them at Hevolution.com Stay tuned... this gets *really* good. Not only great moments in geroscience (aging biology). But great moments in moderation! More at https://www.youtube.com/watch?v=0KT9v_NFfak Thank you Hevolution Foundation: BRAVO! PS- Much better visuals at http://youtube.com/@agingdoc , why n…
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Healthspan

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84. Outlive, by Dr. Peter Attia - Part 8. VO2 max, Strength, and Stability for longevity
12:49
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@michaelsalzle
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Modern Healthspan


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How To Know Your VO2max Level | Prof Martin Gibala Ep2
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Here Dr Gibala talks about what is VO2max, why it is important, how to measure and improve it. Dr Martin Gibala is a Professor at McMaster University where his research examines the effects of exercise at the molecular to whole body level in both healthy individuals and people with chronic diseases. In addition to basic, mechanistic studies on the …
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Here we discuss some themes on @agingdoc at @YouTube . This is part of "Project 49" my committment to myself on my 49th birthday to branch out and apply knowledge and skills in longevity medicine and aging biology towards a broader healthspan moonshot for all. Find me at: agingdoc.com healthspancoaching.com / barzilaiconsulting.com youtube.com/ @ag…
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Agingdoc Podcast (agingdoc.com) - Longevity & Healthspan from Barzilai Consulting


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#3 Aubrey de Grey Part 2
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@agingdoc [ agingdoc.com longevity coach] interview with Aubrey de Grey, PART 2. This is an interview with Aubrey unlike any other. A great time for both of us. It's a lively deep dive into controversy and Aubrey's rebuttals and paradigms for change. You be the judge: 🔑 KEY INTERVIEW MOMENTS BELOW :👇🔎🧐 00:00 Setting the stage our deep-dive 02:44 Au…
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Modern Healthspan


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All You Need To Know About Interval Training | Prof Martin Gibala Ep1
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21:47
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Here Dr Gibala introduces interval training and discusses the various styles, and the benefits. Dr Martin Gibala is a Professor at McMaster University where his research examines the effects of exercise at the molecular to whole body level in both healthy individuals and people with chronic diseases. In addition to basic, mechanistic studies on the…
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Agingdoc Podcast (agingdoc.com) - Longevity & Healthspan from Barzilai Consulting


Today's epsiode is in the spirit of the first Agingdoc Longevity Walk and Meetup, tomorrow 11/20/23 in NYC (Monday 11/20/23, 6pm meeting at The Dakota. Details: https://x.com/agingdoc1/status/1725527792282910895?s=20 Best, David ( "Agingdoc" ). Links: Agingdoc.com ( More info & Longevity Coaching scheduling) Agingdoc Podcast on Youtube (Video) Agin…
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Modern Healthspan


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A Better Way To Raise Glutathione? Human Trial | Dr Nayan Patel Ep3/3
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Here Dr Patel talks about his topical glutathione treatment Glutaryl and the recent trial that was conducted at McGill University. Dr. Nayan Patel is an alumnus of the University Of Southern California School Of Pharmacy, where he now serves as adjunct faculty. A pharmacist for over three decades, Patel is an internationally recognized expert, cons…
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Modern Healthspan


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How Glutathione Changes As We Age | Dr Nayan Patel Ep2
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Here Dr Patel talks about the changes that happen with glutathione as we age, why it is important and what we can do to restore the levels. Dr. Nayan Patel is an alumnus of the University Of Southern California School Of Pharmacy, where he now serves as adjunct faculty. A pharmacist for over three decades, Patel is an internationally recognized exp…
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Modern Healthspan


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Glutathione All You Need To Know | Dr Nayan Patel Ep1
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Here Dr Patel talks about glutathione's major two functions in the body, as an antioxidant and a detoxifier. He also discusses measuring our glutathione levels and what would be a good value to aim for. Dr. Nayan Patel is an alumnus of the University Of Southern California School Of Pharmacy, where he now serves as adjunct faculty. A pharmacist for…
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Modern Healthspan


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My Longevity Protocol | Dr Nichola Conlon Ep4/4
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Here Dr Conlon talks about her personal protocol, that she has decided on as a data driven scientist. We also discuss the next steps for Nuchido as a longevity company. Dr Nichola Conlon is a molecular biologist specialising in the study of cellular aging. After a career in drug development, she founded Nuchido Laboratories to deliver disruptive in…
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Modern Healthspan


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Human Trial : Longevity Supplement Restores NAD & Reverses Biological Age | Dr Nichola Conlon Ep3
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Here Dr Conlon talks about the human trial that she sponsored to evaluate the benefits of Time+ on humans. Dr Nichola Conlon is a molecular biologist specialising in the study of cellular aging. After a career in drug development, she founded Nuchido Laboratories to deliver disruptive innovation in the field of aging, rejuvenation and healthspan. D…
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Modern Healthspan


Here Dr Conlon talks through all the components of Nuchido Time+ and how they fit into the strategy of restoring NAD by activating the cell's natural mechanisms. Dr Nichola Conlon is a molecular biologist specialising in the study of cellular aging. After a career in drug development, she founded Nuchido Laboratories to deliver disruptive innovatio…
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Agingdoc Podcast (agingdoc.com) - Longevity & Healthspan from Barzilai Consulting


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#1 Aubrey de Grey 2023 Part 1
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Aubrey de Grey was my very first guest of the Agingdoc Podcast (before I even gave it a name or was known to be the person behind @,agingdoc1 on Twitter / X) and I think of both Aubrey and Matt Kaeberlein as "Fathers" of the podcast ( with "Mothers to come"). These two were recorded essentially the same time and kicked off this podcast series, each…
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Agingdoc Podcast (agingdoc.com) - Longevity & Healthspan from Barzilai Consulting


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#2 Matt Kaeberlein 2023 Part 1
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Agingdoc interviews Matt Kaeberlein We're just getting warmed up, in this multi-part interview. Matt and I spent 4.5 hours together and I'll be sharing some of the most enlightening moments. Be sure to subscribe not to miss a future release and search for Agingdoc Podcast on Youtube for the best experience: Video edition at http://youtube.com/@agin…
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Agingdoc Podcast (agingdoc.com) - Longevity & Healthspan from Barzilai Consulting


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Who is @agingdoc1?
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🔑Don't miss the footnotes/credit at the bottom! 00:00:00 Introduction @TheSheekeyScienceShow (check out Eleanor's channel!) 00:02:17 Eleanor asks: "Who exactly are you?" 🧐 00:02:37 What am I going to do [for a career]?! 🥼 00:04:51 ME: “I thought a lot of doctors were pretty terrible…”🤯 00:05:43 The Biopsychosocial Model. 📖 00:06:50 Yes, I wrote to …
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Modern Healthspan


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Revive Your NAD Production And Feel Younger | Dr Nichola Conlon Ep1
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Here Dr Conlon explains the biochemistry behind Nuchido Time+ and how it activates the salvage pathway through NAMPT to replenish cellular NAD in sustainable way. Dr Nichola Conlon is a molecular biologist specialising in the study of cellular aging. After a career in drug development, she founded Nuchido Laboratories to deliver disruptive innovati…
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Agingdoc Podcast (agingdoc.com) - Longevity & Healthspan from Barzilai Consulting


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Why an Agingdoc Podcast?
1:29
Agingdoc Podcast overview: This short clip provides a snapshot of what makes this podcast unique in the areas of geroscience, longevity, and lifestyle medicine. It's an off-the-cuff overview by myself (@agingdoc) as a snapshot of my goals and what I hope to do. These videos are an archive of an early stage of "project 49" going public after being h…
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Modern Healthspan


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Longevity - What We Can Learn From Long Lived Mammals | Professor Vera Gorbunova Ep4/4
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Here Professor Gorbunova about the naked mole rat and bowhead whale and what adaptions they have to enable them to live longer. From this she discusses how these adaptions might be translated into interventions for humans. Dr Vera Gorbunova is a biologist. As the Doris Johns Cherry Professor at the University of Rochester, she identified high molec…
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Modern Healthspan


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Hyaluronic Acid Extends Lifespan & Healthspan | Professor Vera Gorbunova Ep3
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Here Professor Gorbunova talks about hyaluronic acid, what it is and why it is different in naked mole rats. She also talks about a trial that she performed where the gene for HA was placed in mice. Finally we talk about how this could be translated into clinical usage. Dr Vera Gorbunova is a biologist. As the Doris Johns Cherry Professor at the Un…
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Modern Healthspan


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How To Activate SIRT6 | Professor Vera Gorbunova Ep2
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Here Professor Gorbunova talks about the two functions of SIRT6, deacetylation and ribosylation, the importance of them and how they can be activated. She also touches on chromatin remodeling and Yamanaka factors. Dr Vera Gorbunova is a biologist. As the Doris Johns Cherry Professor at the University of Rochester, she identified high molecular weig…
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Modern Healthspan


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SIRT6 The Science Behind The Longevity Gene | Professor Vera Gorbunova Ep1
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Here Professor Gorbunova talks about the key activities of SIRT6 that are involved with longevity, particularly DNA repair and the suppression of transposons. Dr Vera Gorbunova is a biologist. As the Doris Johns Cherry Professor at the University of Rochester, she identified high molecular weight hyaluronan as the key mediator of cancer resistance …
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Modern Healthspan


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Immune System Rejuvenation : Path To The Clinic | Dr Stan Wang Ep2
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In this video Dr Wang talks about the current state of trials and how the therapy might eventually look. Stan Wang is Founder and CEO of Thymmune Therapeutics, a cell therapy company working to address high unmet needs across immunology. Previously, Stan was Founding Chief Scientific Officer at Cellino Biotech, where he led R&D and application of i…
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Modern Healthspan


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Promising Therapy To Restoring Our Immune System & Combat Aging | Dr Stan Wang Ep1
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In this episode Dr Wang explains about the thymus gland and his technology for not only restoring the thymus but building new thymuses from iPCSs at scale. Stan Wang is Founder and CEO of Thymmune Therapeutics, a cell therapy company working to address high unmet needs across immunology. Previously, Stan was Founding Chief Scientific Officer at Cel…
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Modern Healthspan


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Tocotrienols Dosage & When To Take | Dr Barrie Tan Ep3/3
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Here Dr Tan talks about tocotrienols in bone health, what an appropriate dosage is and it is better not to take alpha tocopherol with the tocotrienols. Dr. Barrie Tan was formerly an assistant professor at the University of Massachusetts in Amherst (Chemistry, Food Science & Nutrition). His mission at American River Nutrition is to deliver the high…
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Modern Healthspan


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The Amazing Benefits Of Tocotrienols Why They Are Special | Dr Barrie Tan Ep2
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Here Dr Tan talks about the trails that have been run on tocotrienols and the results that have been seen. They have beneficial effects on a number of the markers of metabolic syndrome, such as the lipid panel and liver fat. Dr. Barrie Tan was formerly an assistant professor at the University of Massachusetts in Amherst (Chemistry, Food Science & N…
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Modern Healthspan


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Tocotrienol The Most Effective Form Of Vitamin E | Dr Barrie Tan Ep1
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Here Dr Tan introduces the forms of vitamin E, how they are different and why this matters. He also discusses why a fat based anti-oxidant is required and where alpha tocotrienol is found in nature. Dr. Barrie Tan was formerly an assistant professor at the University of Massachusetts in Amherst (Chemistry, Food Science & Nutrition). His mission at …
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Modern Healthspan


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Brain Health In Scientific Wellness | Dr Nathan Price Ep3
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Dr. Nathan Price is the Chief Scientific Officer of Thorne HealthTech. He is co-author with Lee Hood of The Age of Scientific Wellness, and has written articles for The Wall Street Journal, LA Times, and Scientific American. In 2019, he was named one of 10 Emerging Leaders in Health and Medicine by the National Academy of Medicine, and in 2021 he w…
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Modern Healthspan


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Surprising Results We Saw From The Scientific Wellness Studies | Dr Nathan Price Ep2
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Here Dr Price talks about some of the things that they learned during the pilot exercises, about biomarkers and the gut microbiome. Dr. Nathan Price is the Chief Scientific Officer of Thorne HealthTech. He is co-author with Lee Hood of The Age of Scientific Wellness, and has written articles for The Wall Street Journal, LA Times, and Scientific Ame…
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The Healthspan Project


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Episode#3: Biomarkers and Ways to Reverse Insulin Resistance/Type 2 Diabetes
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We dive into blood biomarkers that help to identify insulin resistance, pre-diabetes and type 2 diabetes and they reasoning behind why these markers are helpful. We then talk about ways to reverse insulin resistance, pre-diabetes and type 2 diabetes. Early detection and slowing down progression of this chronic condition is a great way to preserve h…
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Modern Healthspan


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Optimize Healthspan With Scientific Wellness | Dr Nathan Price Ep1
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Here Dr Price talks about the concepts of Scientific Wellness and the pilot projects that he and his team ran to try this out. Dr. Nathan Price is the Chief Scientific Officer of Thorne HealthTech. He is co-author with Lee Hood of The Age of Scientific Wellness, and has written articles for The Wall Street Journal, LA Times, and Scientific American…
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Here Prof Kaeberlein talks about where he sees longevity going in the near future. We also talk about personalized medicine and whether it is ready for general use. Dr. Kaeberlein’s research interests are focused on biological mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality of life.…
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Modern Healthspan


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Lifestyle Interventions For Healthspan | Prof Matt Kaeberlein Ep5
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Here Prof Kaeberlein discusses his thoughts on exercise and diet. In particular he goes into detail on intermittent fasting, time restricted feeding and calorie restriction. Dr. Kaeberlein’s research interests are focused on biological mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality…
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The Healthspan Project


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Episode #2 Insulin Resistance: A Path To Diabetes
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Diabetes negatively impacts healthspan by increasing the risk of various complications, such as cardiovascular disease, nerve damage, kidney problems, and vision impairment, which can significantly reduce one's overall quality of life as they age. It's a spectrum of disease that starts out with Insulin resistance. Understanding the root cause of In…
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Modern Healthspan


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The Million Molecule Challenge To Find The Next Longevity Treatment | Prof Matt Kaeberlein Ep4
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Here Prof Kaeberlein talks about the million molecule challenge and why he thought that it was necessary. Dr. Kaeberlein’s research interests are focused on biological mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality of life. He has published more than 200 scientific papers, has been…
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Here Prof Kaeberlein talks about the Dog Aging Project a study which is following 100,000's of dogs to understand aging better and includes a RTC of rapamycin related to lifespan. Dr. Kaeberlein’s research interests are focused on biological mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve q…
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Here Prof Kaeberlein talks about the recent paper on taurine deficiency as a driver of aging and makes some comparisons between taurine and rapamycin. Dr. Kaeberlein’s research interests are focused on biological mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality of life. He has publis…
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In this introductory episode of The Healthspan Project, we talk about the reason and passion behind creating this podcast. We touch on the importance of proactive care to preserve longevity and healthspan and we also learn a little bit about the host.Anusha Khan, MD
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Modern Healthspan


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Rapamycin Update What You Need To Know | Prof Matt Kaeberlein Ep1
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Here Prof Kaeberlein provides some updates on rapamycin, in particular the results from the survey based trial that his team ran and thoughts on next steps for the supplement. Dr. Kaeberlein’s research interests are focused on biological mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quali…
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Healthspan

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83. Outlive, by Dr. Peter Attia - Part 7. Exercise, the Centenarian Decathlon, and Zone 2 training
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IG: @michaelsalzle. In this episode, we go into the broad topic of exercise. Exercise is considered the most powerful longevity drug. We review studies that underscore the importance of exercise. We also discuss the centenarian decathlon, and take a deep dive into zone 2 training.
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Modern Healthspan


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What's Next For Probiotic Research | Dr Colleen Cutcliffe Ep4/4
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Here we discuss how to measure your gut microbiome, what the future of probiotic and gut microbiome research may hold and what Dr Cutcliffe's personal regimen is. 🌐Links in this video Colleen Cutcliffe is the Chief Executive Officer and co-founder of Pendulum. She has more than 15 years of experience leading and managing biology teams in academia, …
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Modern Healthspan


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Metabolic Daily Regimen & Benefits | Dr Colleen Cutcliffe Ep3
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Metabolic Daily is a less potent but more available form of the Glucose Control probiotic used in the clinical trial. Dr Colleen Cutcliffe discusses the differences in the formulations, the best time to take and what effects people have seen 🌐Links in this video Colleen Cutcliffe is the Chief Executive Officer and co-founder of Pendulum. She has mo…
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Modern Healthspan


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Human Trial - Probiotic Improves Glucose Control | Dr Colleen Cutcliffe Ep2
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We talk to Dr Colleen Cutcliffe about a clinical trial that they ran with 5 strains of probiotic. We also talk about whether the strains remained resident and what are the best prebiotics for akkermansia. 🌐Links in this video Colleen Cutcliffe is the Chief Executive Officer and co-founder of Pendulum. She has more than 15 years of experience leadin…
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Modern Healthspan


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Akkermansia A Keystone Probiotic That Improves Metabolic & Gut Health | Dr Colleen Cutcliffe Ep1
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We talk to Dr Colleen Cutcliffe about akkermansia muciniphila a probiotic that is involved in Some links are affiliate links so we will earn a commission when they are used to purchase products. 🌐Links in this video Colleen Cutcliffe is the Chief Executive Officer and co-founder of Pendulum. She has more than 15 years of experience leading and mana…
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Modern Healthspan


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A Longevity Expert's Review Of "Taurine Deficiency As a Driver Of Aging" | Prof Joseph Baur
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This is a bonus extra where we asked Dr Baur for his view on the recent taurine longevity paper as he had written a perspective piece in the same publication - Taurine linked with healthy aging https://www.science.org/doi/10.1126/science.adi3025 🌐Links in this video The Baur Lab website https://www.med.upenn.edu/baurlab/ Catch us on YouTube 10% D…
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Modern Healthspan


We talk to Dr Joseph Baur about NMNH and NRH and some of the ways that his lab is working on optimizing NAD boosters by trying to get more of the NAD into the mitochondria and testing on larger animals and in humans. 🌐Links in this video The Baur Lab website https://www.med.upenn.edu/baurlab/ Catch us on YouTube: https://www.youtube.com/c/modernhea…
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Modern Healthspan


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How NAD Precursors Enter Our Cells | Prof Joseph Baur Series 2 Ep4
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We talk to Dr Joseph Baur about how the NAD precursors are absorbed when administered in different formats and what is seen in the biochemistry after that. And some really weird interaction between mammals and bacteria with nicotinamide/nicotinic acid in the gut. 🌐Links in this video The Baur Lab website https://www.med.upenn.edu/baurlab/ Catch us …
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Modern Healthspan


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NAD Boosters Used In Clinical Trials | Prof Joseph Baur Series 2 Ep3
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We talk to Dr Joseph Baur about results from trials of NAD boosters in mice and human trials and possible reasons for why the positive results in mice have not translated to humans. 🌐Links in this video The Baur Lab website https://www.med.upenn.edu/baurlab/ Catch us on YouTube: https://www.youtube.com/c/modernhealthspan 10% Discount on Renue By Sc…
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Modern Healthspan


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How NAD Metabolism Changes With Age | Prof Joseph Baur Series 2 Ep2
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13:04
We talk to Dr Joseph Baur about how NAD metabolism changes with age, especially the role of NAMPT, the consuming enzymes and NAD boosters. 🌐Links in this video The Baur Lab website https://www.med.upenn.edu/baurlab/ Catch us on YouTube: https://www.youtube.com/c/modernhealthspan 10% Discount on Renue By Science products with code MHS https://renueb…
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