Контент предоставлен MasterMedFacts LLC and RR Baliga MD. Весь контент подкастов, включая эпизоды, графику и описания подкастов, загружается и предоставляется непосредственно компанией MasterMedFacts LLC and RR Baliga MD или ее партнером по платформе подкастов. Если вы считаете, что кто-то использует вашу работу, защищенную авторским правом, без вашего разрешения, вы можете выполнить процедуру, описанную здесь https://ru.player.fm/legal.
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Dr RR Baliga's "Got Knowledge Doc" Podkast
Отметить все как (не)прослушанные ...
Manage series 2740117
Контент предоставлен MasterMedFacts LLC and RR Baliga MD. Весь контент подкастов, включая эпизоды, графику и описания подкастов, загружается и предоставляется непосредственно компанией MasterMedFacts LLC and RR Baliga MD или ее партнером по платформе подкастов. Если вы считаете, что кто-то использует вашу работу, защищенную авторским правом, без вашего разрешения, вы можете выполнить процедуру, описанную здесь https://ru.player.fm/legal.
“Got Knowledge Doc” Podkast with Dr. RR Baliga The "Got Knowledge Doc" Podkast, hosted by Dr. Ragavendra R. Baliga, is a knowledge-driven platform designed for physicians and healthcare providers seeking to stay at the forefront of medical science and innovation. With a distinguished career in cardiovascular medicine and academic leadership, Dr. Baliga engages with leading experts to explore cutting-edge research, emerging technologies, and transformative insights in medicine and beyond. Each episode delves into topics such as cardiology, precision medicine, artificial intelligence in healthcare, epigenetics, and medical ethics—making complex advancements accessible and relevant to clinical practice. Importantly, this podcast is purely educational and does not provide medical advice or clinical opinions. Join Dr. Baliga and his esteemed guests as they navigate the evolving landscape of medical knowledge, empowering healthcare professionals with evidence-based insights that shape the future of patient care.
…
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385 эпизодов
Отметить все как (не)прослушанные ...
Manage series 2740117
Контент предоставлен MasterMedFacts LLC and RR Baliga MD. Весь контент подкастов, включая эпизоды, графику и описания подкастов, загружается и предоставляется непосредственно компанией MasterMedFacts LLC and RR Baliga MD или ее партнером по платформе подкастов. Если вы считаете, что кто-то использует вашу работу, защищенную авторским правом, без вашего разрешения, вы можете выполнить процедуру, описанную здесь https://ru.player.fm/legal.
“Got Knowledge Doc” Podkast with Dr. RR Baliga The "Got Knowledge Doc" Podkast, hosted by Dr. Ragavendra R. Baliga, is a knowledge-driven platform designed for physicians and healthcare providers seeking to stay at the forefront of medical science and innovation. With a distinguished career in cardiovascular medicine and academic leadership, Dr. Baliga engages with leading experts to explore cutting-edge research, emerging technologies, and transformative insights in medicine and beyond. Each episode delves into topics such as cardiology, precision medicine, artificial intelligence in healthcare, epigenetics, and medical ethics—making complex advancements accessible and relevant to clinical practice. Importantly, this podcast is purely educational and does not provide medical advice or clinical opinions. Join Dr. Baliga and his esteemed guests as they navigate the evolving landscape of medical knowledge, empowering healthcare professionals with evidence-based insights that shape the future of patient care.
…
continue reading
385 эпизодов
Semua episod
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Dr RR Baliga's "Got Knowledge Doc" Podkast

🧪 A randomized clinical trial in older adults (65+) found that Vitamin K2 (menaquinone-7, 180 μg/day) significantly reduced nocturnal leg cramps in terms of frequency, severity, and duration—with no adverse effects reported. 🌙🦵💊 This safe (?), over-the-counter supplement may offer a simple, science-backed solution for painful nighttime cramps—avoid it if you’re on warfarin. 🚫💉✅…
📊 Too much sitting hurts the heart. 🧍♂️ Ajufo et al. (2024) tracked 89,530 people using accelerometers and found that 🪑 >10.6 hours/day of sitting sharply increases the risk of ❤️ heart failure, 💔 heart attacks, 💓 AFib, and ⚰️ cardiovascular death. 🏃 Even active people aren’t fully protected. 🔁 Replacing just 30 minutes of sitting with movement—🕺 light or 🏋️♂️ vigorous—reduces risk. 🧠 The takeaway? Sit less, move more, live longer.…
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Dr RR Baliga's "Got Knowledge Doc" Podkast

🧑⚕️💔 Young, Fit… Gone? Every year, thousands of seemingly healthy young adults suffer sudden cardiac arrest (SCA) outside the hospital. 📉 Only 9–16% survive to discharge — yet 90% of survivors leave with good brain function. 🔍 Many have hidden risk factors — hypertension, diabetes, even genetic arrhythmia syndromes like Brugada or Long QT. ⚡ Rapid CPR, AED use, and targeted evaluation (ECG, imaging, genetics) save lives and prevent recurrence. 🧬 Survivors—and their families—may carry silent genetic signals. 🔁 The takeaway? SCA isn’t random. It’s a warning shot. One we can catch—if we’re ready.…
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Dr RR Baliga's "Got Knowledge Doc" Podkast

1 Dr. RR Baliga’s Philosophical Discourses: Gautama Buddha (India, c. 563–483 BCE) – Founder of Buddhism 3:13
Siddhartha Gautama, known as the Buddha (“the awakened one”), was a spiritual teacher who founded Buddhism in the 5th or 6th century BCE in South Asia. His core teachings include the Middle Way, the Four Noble Truths, and the Noble Eightfold Path, emphasizing mindfulness, ethics, and liberation from suffering.…
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Dr RR Baliga's "Got Knowledge Doc" Podkast

•Olive. Canola. Soybean. •Not just flavor—they’re lifelines. 🌱 •Every 10g a day drops mortality by 16%. •They don’t just cook food—they cook up longevity? 🔥⏳
🧬 Your mother’s X chromosome may shape how your brain ages. In female mice, when only the maternal X chromosome (Xm) is active, older animals show worse memory 🧠🕳️ than those with random X-inactivation. This is due to imprinted genes — some only expressed from the paternal X (Xp) — which are silent when Xm dominates. 🧠💡 Using CRISPR–Cas9, researchers reactivated 3 Xm-silent genes ( Sash3, Tlr7, Cysltr1 ) and saw improved memory and mitochondrial function ⚡🔋. 👩🔬 This highlights inter-female variation in aging and memory — and suggests that epigenetic inheritance from mothers may shape how well we remember… or forget. 🧓🧠❓…
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Dr RR Baliga's "Got Knowledge Doc" Podkast

🔬 Confounding, Clarity, and Causality Family-based biobanks 🧬 are the next frontier in genetic research—tackling bias 🧠, boosting causal inference 🎯, and revealing insights hidden in the noise of population studies 🌍. It’s not just about big data—it’s about better data 👨👩👧👦.
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Dr RR Baliga's "Got Knowledge Doc" Podkast

🧠 Brain Aging & Research Advances 🔍 Key Findings: • Brain Age Gap (BAG): Difference between estimated and chronological brain age. • 64 genes identified as influencing brain aging. • 13 proteins in blood linked to accelerated/slowed brain aging. 🩺 Potential Interventions: • 13 anti-aging drugs (e.g., Rapamycin, Dasatinib) show promise in slowing decline. • Plasma proteomics reveals key biomarkers for early intervention. 🌍 Influencing Factors: • Socioeconomic status, pollution, and gender inequality impact brain aging. • Functional connectivity decline linked to cognitive disorders. 🚀 Future Directions: • Clinical trials needed for drug validation. • Genetic & proteomic studies should expand to diverse populations.…
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Dr RR Baliga's "Got Knowledge Doc" Podkast

The blood-brain barrier (BBB) 🛡️ protects the brain from harmful molecules but weakens with aging 🧓, leading to neuroinflammation 🔥 and cognitive decline 📉. Mucins 🧬, slippery proteins in the glycocalyx 🏗️, help maintain BBB integrity 🧠. This study found that mucin loss 🚨 increases BBB permeability, allowing toxins to enter. Using gene therapy 🧪, researchers restored mucins, improving memory and learning 📈 in aged mice. This breakthrough suggests that mucin-based treatments 🏥 could prevent neurodegenerative diseases like Alzheimer’s and Parkinson’s 🎯 while also enhancing brain drug delivery 🚀.…
🧠 Migraine is a complex neurological disorder affecting 1 billion people worldwide. Historically misunderstood, it was once seen as a vascular or psychological issue but is now recognized as a brain network dysfunction involving the hypothalamus and limbic system. 💊 Gepants and CGRP blockers have revolutionized treatment, though they only work for some patients. Triggers like stress, hormones, diet, and environmental factors play a role, and genetics influences susceptibility. 🤖 AI-driven research is helping predict attacks and personalize treatments, while new studies are shifting focus beyond headaches to cognitive and systemic symptoms. Future research aims to uncover additional pathways and improve long-term management. 🚀…
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Dr RR Baliga's "Got Knowledge Doc" Podkast

Alcohol is a proven carcinogen 🚨, increasing the risk of at least 7 cancers (mouth, throat, breast, liver, etc.) 🦠💀. Even small amounts (5g ethanol/day) raise cancer risk, with no safe threshold 📊🚫. Similarly, exceeding 14 drinks/week (men) or 7 (women) raises CHD risk by up to 43% 💔📈. Past claims of heart benefits from moderate drinking are now being challenged 🧐❓. Best advice? Limit or avoid alcohol for better long-term health 🚫🥃✔️.…
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Dr RR Baliga's "Got Knowledge Doc" Podkast

1 Dr. RR Baliga’s Philosophical Discourses: Heraclitus (Greece, c. 535–475 BCE) – Pre-Socratic Philosopher 3:29
Heraclitus (c. 500 BC), a pre-Socratic philosopher from Ephesus, is renowned for his doctrine of perpetual change and the unity of opposites, encapsulated in the phrase “Everything flows” and “No man ever steps in the same river twice.” His concept of logos as the rational order of the universe influenced ancient and modern philosophy, including thinkers like Plato, Aristotle, and Hegel. Known as “the dark” philosopher for his cryptic style and paradoxical ideas, Heraclitus viewed strife as fundamental to justice and saw fire as the primal element of existence. His legacy endures in the study of cosmology, metaphysics, and dialectics.…
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Dr RR Baliga's "Got Knowledge Doc" Podkast

☕ Coffee & Gut Microbiome 🦠 🔬 A multi-cohort study (N = 22,867) found a strong link between coffee consumption and the gut bacterium Lawsonibacter asaccharolyticus. 🧪 Metabolomics identified key coffee-derived metabolites like quinic acid, hippurate, and trigonelline. 📊 Machine learning (AUC = 0.89) confirmed microbiome composition predicts coffee intake. 🧫 In vitro studies showed coffee stimulates L. asaccharolyticus growth. ⚙️ Findings suggest polyphenols in coffee shape gut microbiota and metabolic pathways. 🚀 Future research aims to explore dose-dependent effects, health benefits, and microbiome-driven nutrition.…
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Dr RR Baliga's "Got Knowledge Doc" Podkast

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Dr RR Baliga's "Got Knowledge Doc" Podkast

🔬 Antioxidants & Health: Myths vs. Reality ❌🍊💊 Despite popular belief, vitamins C & E do not reduce the risk of cancer, heart disease, or chronic illness 🚫❤️. High doses of vitamin A increase the risk of hip fractures & prostate cancer ⚠️🦴, while vitamin E is linked to respiratory infections, prostate cancer, and even death 😷❌. However, a specific combination of antioxidants (C, E, zinc, copper, lutein, zeaxanthin) slows vision loss in age-related macular degeneration (AMD) 👁️🧡. A multiomic study identified GSTO1 as the best biomarker for zinc deficiency 🧪🔍, but further validation is needed. Takeaway? Antioxidants have specific benefits, but not as universal disease preventers! ⚖️🚀…
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