Episode 15. Management of Newly Diagnosed DLBCL (Including Bonus ASH22 Updates)

Blood Cancer Talks

Контент предоставлен Rajshekhar Chakraborty and Ashwin Kishtagari, Rajshekhar Chakraborty, Ashwin Kishtagari, and Edward Cliff. Весь контент подкастов, включая эпизоды, графику и описания подкастов, загружается и предоставляется непосредственно компанией Rajshekhar Chakraborty and Ashwin Kishtagari, Rajshekhar Chakraborty, Ashwin Kishtagari, and Edward Cliff или ее партнером по платформе подкастов. Если вы считаете, что кто-то использует вашу работу, защищенную авторским правом, без вашего разрешения, вы можете выполнить процедуру, описанную здесь https://ru.player.fm/legal.

2y ago 53:44

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In this episode, we discuss the management of newly diagnosed DLBCL with Dr. Pallawi Torka. We also have a few bonus ASH22 updates on DLBCL. Links to articles and abstracts discussed in the episode are as follows:

1. A comprehensive review article on DLBCL:

https://pubmed.ncbi.nlm.nih.gov/33657296/

2. RCT testing CHOP vs Three Intensive Regimens in DLBCL:

https://www.nejm.org/doi/full/10.1056/nejm199304083281404

3. RCT testing R-CHOP vs CHOP in DLBCL in older adults:

https://www.nejm.org/doi/full/10.1056/nejmoa011795

4. RCT testing R-CHOP vs CHOP in young (MINT):

https://pubmed.ncbi.nlm.nih.gov/21940214/

5. PHOENIX trial: R-CHOP +/- Ibrutinib:

https://pubmed.ncbi.nlm.nih.gov/30901302/

6. R-CHOP +/- Lenalidomide (ECOG-ACRIN E1412):

https://pubmed.ncbi.nlm.nih.gov/33555941/

7. R-CHOP vs Pola-R-CHP (POLARIX Trial):

https://www.nejm.org/doi/full/10.1056/NEJMoa2115304

8. Comparison of 3 IPI scores in DLBCL:

https://ashpublications.org/blood/article/135/23/2041/452696

9. RCT testing R-CHOP vs Dose-Adjusted R-EPOCH (CALGB 50303):

https://ascopubs.org/doi/full/10.1200/JCO.18.01994

10. Timing of CNS Prophylaxis in DLBCL:

https://pubmed.ncbi.nlm.nih.gov/34995350/

11. RCT testing R-CHOP vs R-CHOP + Bortezomib (REMoDL-B):

https://pubmed.ncbi.nlm.nih.gov/30948276/

12. Interim PET in DLBCL?

https://ashpublications.org/bloodadvances/article/5/9/2375/475850

13. RCTs in Limited Stage DLBCL:

CHOP x 8 vs CHOP x 3 + XRT (S8736):

https://ascopubs.org/doi/10.1200/JCO.2015.65.4582

CHOP x 4 + Rituximab x 6 vs R-CHOP x 6 (FLYER):

https://pubmed.ncbi.nlm.nih.gov/31868632/

PET-adapted therapy with R-CHOP (S1001):

https://pubmed.ncbi.nlm.nih.gov/32658627/

14. ASH 2022 updates:

REMoDL-B update: https://ashpublications.org/blood/article/140/Supplement%201/1770/493225

Glofitamab update: https://ashpublications.org/blood/article/140/Supplement%201/1062/491024

Epcoritamab update: https://ashpublications.org/blood/article/140/Supplement%201/9443/488543

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