Genetic Innovations: From Gene Therapy to Germline Genome Editing

MedChat

Genetic Innovations: From Gene Therapy to Germline Genome Editing

Evaluation and Credit: https://www.surveymonkey.com/r/MedChat69

Target Audience This activity is targeted toward primary care physicians and advanced providers.

Statement of Need This program will provide an overview of recent innovations in genetics, highlighting gene therapy and germline genome editing. The discussion will include a review of what it is as well as applications andfuture trends in gene therapy.

Objectives At the conclusion of this offering, the participant will be able to:

• Define gene therapy, germline genome editing and precision medicine.
• Review the applications of gene therapy and germline genome editing.
• Explain the differences and clinical implications of whole genome sequencing and whole exome sequencing.
• Discuss future trends of gene therapy and germline genome editing.

ModeratorMark McDonald, M.D., FAAP Medical Director Norton Children’s Hospital and Norton Children’s Medical Center Professor Department of Pediatrics, Critical Care UofL School of Medicine Louisville, Kentucky

SpeakerKyle B. Brothers, M.D., Ph.D. Pediatrician and Bioethicist Chief Scientific Officer Norton Children's Research Institute affiliated with the UofL School of Medicine Louisville, Kentucky

Moderator, Speaker and Planner Disclosures The planners and moderator of this activity do not have any relevant financial relationships with ineligible companies to disclose. The speaker Kyle Brothers, M.D., Ph.D., discloses a relevant financial relationship with Invitae in research. This relationship has been mitigated.

Commercial Support There was no commercial support for this activity.

Physician Credits Accreditation Norton Healthcare is accredited by the Kentucky Medical Association to provide continuing medical education for physicians.

Designation Norton Healthcare designates this enduring material for a maximum of .50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

For more information about continuing medical education, please send an email to [e-mail].

Nursing CreditsNorton Healthcare Institute for Education and Development is approved with distinction as a provider of nursing continuing professional development by the South Carolina Nurses Association, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation. This continuing professional development activity has been approved for .50 contact hours. In order for nursing participants to obtain credits, they must claim attendance by attesting to the number of hours in attendance.

For more information related to nursing credits, contact Sally Sturgeon, DNP, RN, SANE-A, AFN-BC at [phone] or [e-mail].

Resources for Additional Study:

Changes in opinions about human germline gene editing as a result of the Dutch DNA-dialogue project https://pubmed.ncbi.nlm.nih.gov/35551502/

Altered lipid metabolism and the development of metabolic-associated fatty liver disease https://pubmed.ncbi.nlm.nih.gov/38484227/

Also listen to Norton Healthcare’s podcast Stronger After Stroke. This podcast, produced by the Norton Neuroscience Institute, discusses difficult topics, answers frequently asked questions and provides survivor stories that provide hope. Hear from stroke survivors and medical specialists about being stronger after stroke. Listen on your favorite podcast platform.

Norton Healthcare, a not for profit health care system, is a leader in serving adult and pediatric patients throughout Greater Louisville, Southern Indiana, the commonwealth of Kentucky and beyond. Five Louisville-based hospitals and three hospitals in Southern Indiana, provide inpatient and outpatient general care as well as specialty care including heart, neuroscience, cancer, orthopedic, women’s and pediatric services. A strong research program provides access to clinical trials in a multitude of areas. More information about Norton Healthcare is available at NortonHealthcare.com.

Date of Original Release | Aug. 2024; Information is current as of the time of recording.

Course Termination Date | Aug. 2026

Contact Information | Center for Continuing Medical Education; [phone] or [e-mail]

Podcast editing and production by: www.unmuteaudio.com